SCHEMBL186351

SCHEMBL186351

[O]c1c(F)c(F)c(C(F)(F)F)c(F)c1F

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.40
TSHR P16473 1/20 0.40
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1053501 0.85 SMN1; SMN2 (0.34) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL312355 0.83 SMN1; SMN2 (0.42) SMN1; SMN2TSHRMEN1KMT2A
Perfluorotoluene SCHEMBL308464 0.79 SMN1; SMN2 (0.41) SMN1; SMN2TSHRMEN1KMT2A
Perfluorotoluene SCHEMBL28273865 0.76 SMN1; SMN2 (0.39) SMN1; SMN2TSHRMEN1KMT2A
Perfluorotoluene SCHEMBL28760715 0.76 SMN1; SMN2 (0.39) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL3168128 0.76 SMN1; SMN2 (0.39) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL1998599 0.75 SMN1; SMN2 (0.37) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL24254677 0.73 SMN1; SMN2 (0.38) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL28505018 0.73 SMN1; SMN2 (0.38) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL312356 0.72 SMN1; SMN2 (0.36) SMN1; SMN2TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12029120-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-07-02 US disclosed
US-20240155942-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2024-05-09 US disclosed
US-11944009-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-03-26 US disclosed
EP-3974433-B1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND, AND ELECTRONIC APPLIANCE IDEMITSU KOSAN CO (JP) 2024-02-21 EP disclosed
CN-111372918-B Compound, material for organic electroluminescent element, and electronic device 出光兴产株式会社 2023-09-05 CN disclosed
US-20230048761-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-16 US disclosed
US-20230050369-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-16 US disclosed
US-20230011206-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC APPLIANCE IDEMITSU KOSAN CO.,LTD. (JP) 2023-01-12 US disclosed
EP-4108661-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE Idemitsu Kosan Co.,Ltd. (JP) 2022-12-28 EP disclosed
EP-4108660-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC APPLIANCE Idemitsu Kosan Co.,Ltd. (JP) 2022-12-28 EP disclosed
US-8778510-B2 Pyrromethene-boron complex compounds and organic electroluminescent elements using same IDEMITSU KOSAN CO., LTD. (JP) 2014-07-15 US disclosed
EP-2402351-B1 PYRROMETHENE-BORON COMPLEX COMPOUNDS AND ORGANIC ELECTRO- LUMINESCENT ELEMENTS USING SAME IDEMITSU KOSAN CO (JP) 2013-10-09 EP disclosed
WO-2012133921-A1 CATALYST FOR OLEFIN OLIGOMERIZATION AND METHOD FOR PRODUCING α-OLEFIN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 WO disclosed
US-20120037890-A1 PYRROMETHENE-BORON COMPLEX COMPOUNDS AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME MITSUI CHEMICALS, INC. 2012-02-16 US disclosed
EP-2402351-A1 PYRROMETHENE-BORON COMPLEX COMPOUNDS AND ORGANIC ELECTRO- LUMINESCENT ELEMENTS USING SAME Idemitsu Kosan Co., Ltd. (JP) 2012-01-04 EP disclosed
EP-0633893-B1 17-SUBSTITUTED STEROIDS USEFUL IN CANCER TREATMENT BTG INT LTD (GB) 1999-11-24 EP disclosed
US-5618807-A Method for preparing 17-substituted steroids useful in cancer treatment BRITISH TECHNOLOGY GROUP LIMITED (GB) 1997-04-08 US disclosed
US-5604213-A STEROID DEPENDENT CANCERS SUCH AS PROSTATE AND BREAST CANCER BRITISH TECHNOLOGY GROUP LIMITED (GB) 1997-02-18 US disclosed
EP-0633893-A1 17-SUBSTITUTED STEROIDS USEFUL IN CANCER TREATMENT BRITISH TECHNOLOGY GROUP LTD (GB) 1995-01-18 EP disclosed
WO-1993020097-A1 17-SUBSTITUTED STEROIDS USEFUL IN CANCER TREATMENT BRITISH TECHNOLOGY GROUP LTD. (GB) 1993-10-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120037890-A1 PYRROMETHENE-BORON COMPLEX COMPOUNDS AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME LEF1, ZRANB2, AFF1 SMN1; SMN2 4195/4885TSHR 1693/4885MEN1 243/4885
US-11944009-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device LEF1, RER1, OR10J3 SMN1; SMN2 2782/4885TSHR 2294/4885MEN1 837/4885
US-12029120-B2 Organic electroluminescence element and electronic device RPS10, H1-10, OR10J3 SMN1; SMN2 3913/4885TSHR 3535/4885MEN1 1431/4885
US-20240155942-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RPS10, H1-10, OR10J3 SMN1; SMN2 3913/4885TSHR 3535/4885MEN1 1431/4885
US-20230011206-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC APPLIANCE MLX, H1-0, RER1 SMN1; SMN2 2393/4885TSHR 1256/4885MEN1 2330/4885
US-20230048761-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE CCNE2, EMC2, CHRM2 SMN1; SMN2 1806/4885TSHR 2533/4885MEN1 1370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.