Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 6/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3423361 | 0.86 | CA14 (0.38) | CPB2CA14CA1CA12CA2 | |
| SCHEMBL3422485 | 0.85 | CPB2 (0.33) | CPB2CA14CA1CA12CA2 | |
| SCHEMBL24271052 | 0.83 | HDAC6 (0.33) | CPB2CA14CA1CA12CA2 | |
| SCHEMBL3422989 | 0.81 | DGAT1 (0.38) | CPB2CA14CA1CA12CA2 | |
| SCHEMBL3422429 | 0.80 | DGAT1 (0.39) | CPB2CA14CA1CA12CA2 | |
| SCHEMBL17049571 | 0.79 | HDAC6 (0.33) | CA14CA1CA12CA2CA7 | |
| SCHEMBL12336689 | 0.79 | HDAC6 (0.33) | CA14CA1CA12CA2CA7 | |
| SCHEMBL14551606 | 0.79 | CTSK (0.33) | CPB2CA14CA1CA12CA2 | |
| SCHEMBL13715964 | 0.77 | CA14 (0.39) | CA14CA1CA12CA2CA7 | |
| SCHEMBL12324239 | 0.77 | HDAC6 (0.36) | CPB2CA14CA1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065709-A2 | HYDROXAMIC ACID DERIVATIVES, PREPARATION AND THERAPEUTIC USES THEREOF | KHAN AMIN (US) | 2010-06-10 | — | — | WO | disclosed |