Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.45 |
| ▸ | GPR39 | O43194 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1029414 | 0.81 | CDK1 (0.51) | CTSKPIM1PIM3KDM4EMAP4K4 | |
| SCHEMBL12898597 | 0.72 | CCNT1 (0.61) | PRKD1KDM4EALDH1A1L3MBTL1CCNT1 | |
| SCHEMBL12898694 | 0.71 | CCNT1 (0.58) | PRKD1LMNASMN1; SMN2CCNT1CDC7 | |
| SCHEMBL3391570 | 0.70 | CYP1A2 (0.46) | ALDH1A1MAP4K4LMNAIRAK4 | |
| SCHEMBL25158454 | 0.69 | CDC7 (0.47) | PIM1PIM3MAP4K4MAPK10IRAK4 | |
| SCHEMBL1718265 | 0.68 | PRKCI (0.52) | PIM1PIM3PIM2MAP4K4IRAK4 | |
| SCHEMBL8942450 | 0.67 | RIPK1 (0.55) | PIM1PIM3PIM2MAP4K4IRAK4 | |
| SCHEMBL7956048 | 0.67 | KARS1 (0.57) | PRKD1CCNT1 | |
| SCHEMBL1579219 | 0.67 | PRKD1 (0.71) | PRKD1 | |
| SCHEMBL29632728 | 0.67 | CTSK (0.59) | CNR1CTSKGPR39MAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010052448-A2 | FUSED PYRAZINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2010-05-14 | — | — | WO | disclosed |