Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 6/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 8/20 | 0.41 |
| ▸ | RORA | P35398 | 3/20 | 0.40 |
| ▸ | RORB | Q92753 | 3/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2512045 | 0.74 | APOBEC3G (0.58) | APOBEC3GRORCNR1H3NR1H2NR1I2 | |
| SCHEMBL9657376 | 0.74 | APOBEC3G (0.52) | APOBEC3GTDP1ALDH1A1HSD11B1 | |
| SCHEMBL10689063 | 0.72 | TBXA2R (0.48) | APOBEC3GNR1H3NR1H2NR1I2TDP1 | |
| SCHEMBL27794695 | 0.71 | APOBEC3G (0.54) | APOBEC3GRORCNR1H3NR1H2NR1I2 | |
| SCHEMBL1868116 | 0.71 | APOBEC3G (0.54) | APOBEC3GRORCNR1H3NR1H2NR1I2 | |
| SCHEMBL1768495 | 0.71 | APOBEC3G (0.54) | APOBEC3GRORCNR1H3NR1H2NR1I2 | |
| SCHEMBL3483110 | 0.71 | CCR5 (0.53) | APOBEC3GNR1H3TDP1ALDH1A1MAPT | |
| SCHEMBL6917666 | 0.69 | NR1H3 (0.69) | APOBEC3GRORCNR1H3NR1H2NR1I2 | |
| SCHEMBL3482968 | 0.69 | LMNA (0.60) | APOBEC3GRORCNR1I2MAPT | |
| SCHEMBL11220474 | 0.69 | APOBEC3G (0.52) | APOBEC3GRORCNR1H3NR1H2NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2148881-A1 | FLUORINATED LANTHANIDE PROBES FOR 19F MAGNETIC RESONANCE APPLICATIONS | UNIVERSITY OF DURHAM (GB) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008132433-A1 | FLUORINATED LANTHANIDE PROBES FOR 19F MAGNETIC RESONANCE APPLICATIONS | UNIVERSITY OF DURHAM (GB) | 2008-11-06 | — | — | WO | disclosed |