Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482749 | 0.88 | LMNA (0.57) | APOBEC3GKMT2ALMNAHTTTDP1 | |
| SCHEMBL3483545 | 0.86 | TAS2R14 (0.58) | KMT2AHTTTDP1CNR2TAS2R14 | |
| SCHEMBL3483000 | 0.85 | TDP1 (0.54) | LMNAHTTTDP1CNR2MAPK1 | |
| SCHEMBL3483317 | 0.83 | TAS2R14 (0.59) | LMNAHTTTAS2R14 | |
| SCHEMBL3482729 | 0.82 | TDP1 (0.65) | KMT2ALMNAHTTTDP1CNR2 | |
| SCHEMBL3483152 | 0.79 | PTGES (0.51) | KMT2ACNR2TAS2R14MEN1ALDH1A1 | |
| SCHEMBL25245992 | 0.78 | GLA (0.59) | LMNAHTTCNR2TAS2R14SMN1; SMN2 | |
| SCHEMBL3483110 | 0.78 | CCR5 (0.53) | APOBEC3GKMT2ALMNAHTTTDP1 | |
| SCHEMBL3482958 | 0.78 | PTGES (0.53) | KMT2ACNR2TAS2R14MEN1ALDH1A1 | |
| SCHEMBL2058156 | 0.77 | LMNA (0.70) | APOBEC3GKMT2ALMNAHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471783-A1 | POLYMETHINE COMPOUNDS, AND POLYMER COMPOSITIONS CONTAINING THEM | EASTMAN KODAK COMPANY (US) | 1992-02-26 | — | — | EP | claimed |
| US-4994512-A | Photostabilizers for vecerage and food containers of polyesters or polycarbonate; ultraviolet radiation resistance | EASTMAN KODAK COMPANY (US) | 1991-02-19 | — | — | US | claimed |
| EP-0401128-A1 | Polymethine compounds and polymer compositions containing them | EASTMAN KODAK COMPANY (US) | 1990-12-05 | — | — | EP | claimed |
| WO-1990013597-A1 | POLYMETHINE COMPOUNDS, AND POLYMER COMPOSITIONS CONTAINING THEM | EASTMAN KODAK COMPANY (US) | 1990-11-15 | — | — | WO | claimed |
| EP-0273280-A2 | Condensation polymer containing the residue of a poly-methine compound and shaped articles produced therefrom | EASTMAN CHEMICAL COMPANY (US) | 1988-07-06 | — | — | EP | claimed |
| US-4749774-A | UNSATURATED POLYESTERS | EASTMAN KODAK COMPANY (US) | 1988-06-07 | — | — | US | claimed |
| EP-0471783-A1 | POLYMETHINE COMPOUNDS, AND POLYMER COMPOSITIONS CONTAINING THEM | EASTMAN KODAK COMPANY (US) | 1992-02-26 | — | — | EP | disclosed |
| US-4994512-A | Photostabilizers for vecerage and food containers of polyesters or polycarbonate; ultraviolet radiation resistance | EASTMAN KODAK COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| WO-1990013597-A1 | POLYMETHINE COMPOUNDS, AND POLYMER COMPOSITIONS CONTAINING THEM | EASTMAN KODAK COMPANY (US) | 1990-11-15 | — | — | WO | disclosed |
| US-4749774-A | UNSATURATED POLYESTERS | EASTMAN KODAK COMPANY (US) | 1988-06-07 | — | — | US | disclosed |