Ethylene Glycol

Ethylene Glycol

SCHEMBL3422304

NC(=O)CCC(=O)NN1C(=O)CCC1=O.OCCO

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.33
ALOX12 P18054 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL122496 0.95 KDM4E (0.38) KDM4EALDH1A1ALOX12TSHR
Methoxymethane SCHEMBL7647288 0.88 KDM4E (0.40) KDM4EALDH1A1ALOX12TSHR
SCHEMBL26099241 0.86 KDM4E (0.37) KDM4EALDH1A1ALOX12TSHR
SCHEMBL29018280 0.74 KDM4E (0.45) KDM4EALDH1A1ALOX12
SCHEMBL27165394 0.72 KDM4E (0.35) KDM4EALDH1A1ALOX12
SCHEMBL8380249 0.71 KDM4E (0.37) KDM4EALDH1A1ALOX12TSHR
SCHEMBL27759259 0.70 KDM4E (0.38) KDM4EALDH1A1ALOX12TSHR
SCHEMBL13182184 0.70 KDM4E (0.44) KDM4EALDH1A1ALOX12
SCHEMBL215902 0.70 KDM4E (0.37) KDM4EALDH1A1ALOX12
Ethylene Glycol SCHEMBL4902639 0.69 TSHR (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7129209-B2 Use of hydrophobic crosslinking agents to prepare crosslinked biomaterial compositions ANGIOTECH PHARMACEUTICLAS (US), INC. (US) 2006-10-31 US claimed
US-6962979-B1 Crosslinkable biomaterial compositions containing hydrophobic and hydrophilic crosslinking agents COHESION TECHNOLOGIES, INC. (US) 2005-11-08 US claimed
US-20020052572-A1 Resorbable anastomosis stents and plugs and their use in patients COHESION TECHNOLOGIES, INC. 2002-05-02 US claimed
US-10004587-B2 Macroporous 3-D scaffolds for tissue engineering THE BOARD OF TRUSTEES FOR THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2018-06-26 US disclosed
US-20160331508-A1 MACROPOROUS 3-D SCAFFOLDS FOR TISSUE ENGINEERING THE BOARD OF TRUSTEES FOR THE LELAND STANFORD JUNIOR UNIV (US) 2016-11-17 US disclosed
US-9402710-B2 Macroporous 3-D scaffolds for tissue engineering THE BOARD OF TRUSTEES FOR THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2016-08-02 US disclosed
US-20140017284-A1 Macroporous 3-D scaffolds for tissue engineering THE BOARD OF TRUSTEES FOR THE LELAND STANFORD JUNIOR UNIVERSITY 2014-01-16 US disclosed
EP-2162155-A2 HYDROGEL MATERIALS Gore Enterprise Holdings, Inc. (US) 2010-03-17 EP disclosed
WO-2008143957-A2 HYDROGEL MATERIALS GORE ENTERPRISE HOLDINGS, INC. (US) 2008-11-27 WO disclosed
US-20080287633-A1 Hydrogel Materials W. L. GORE & ASSOCIATES, INC. 2008-11-20 US disclosed
EP-0638112-B1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING & MFG (US) 2002-08-07 EP disclosed
EP-0792255-B1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING & MFG (US) 2001-02-28 EP disclosed
EP-0792255-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-03 EP disclosed
WO-1996015092-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-23 WO disclosed
US-5482650-A Liquid crystal compounds having perfluoroether terminal portions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-01-09 US disclosed
US-5437812-A Achiral and having low-temperature smectic mesophases or or latent smectic mesophases; used in mixtures with fluorinated liquid crystals; low birefringence and viscosity; high speed switches; stability MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-08-01 US disclosed
EP-0638112-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-02-15 EP disclosed
US-5262082-A Ferroelectric liquid crystal compounds having perfluoroether terminal portions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-16 US disclosed
WO-1993022396-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-11 WO disclosed