SCHEMBL342258

SCHEMBL342258

CCc1cc(C2CCCC2)c(N)cc1N

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.37
JAK2 O60674 1/20 0.35
JAK1 P23458 1/20 0.35
JAK3 P52333 1/20 0.35
TDO2 P48775 2/20 0.34
EPHX2 P34913 1/20 0.33
MAPT P10636 2/20 0.32
NUDT1 P36639 1/20 0.32
BACE1 P56817 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CHEK1 O14757 1/20 0.32
CCNA2 P20248 1/20 0.32
CDK2 P24941 1/20 0.32
CCNA1 P78396 1/20 0.32
ALDH1A1 P00352 2/20 0.31
CYP1A2 P05177 1/20 0.31
ALOX15 P16050 1/20 0.31
CASP7 P55210 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30301253 1.00 HTR2A (0.37) HTR2AJAK2JAK1JAK3TDO2
SCHEMBL168792 0.80 TDO2 (0.43) HTR2ATDO2MAPTNUDT1BACE1
SCHEMBL31587049 0.76 AAK1 (0.30)
SCHEMBL25558929 0.75 EPHX2 (0.35) EPHX2BACE1
SCHEMBL9819248 0.75 CYP3A4 (0.41) HTR2AJAK2JAK1JAK3TDO2
SCHEMBL118865 0.72 ALDH1A1 (0.46) MAPTBACE1ALDH1A1CYP1A2ALOX15
SCHEMBL24172412 0.71 BACE1 (0.40) HTR2AJAK2JAK1JAK3TDO2
SCHEMBL342627 0.70 TDO2 (0.34) HTR2ATDO2PTGDR2
SCHEMBL24328529 0.70 HTR1D (0.39) CYP1A2ALOX15
SCHEMBL15173969 0.70 L3MBTL1 (0.43) TDO2CHEK1CCNA2CDK2CCNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3938416-B1 POLYURETHANE COATING COMPOSITIONS AND THEIR USE AS GEL COATS COVESTRO LLC (US) 2025-09-10 EP disclosed
US-20240376246-A1 ONE-POT PROCESS FOR THE PRODUCTION OF POLYCARBODIIMIDE CURED POLYMERS BASF SE (DE) 2024-11-14 US disclosed
US-20240343941-A1 DUAL-CURE RESIN COMPOSITION COMPRISING URETDIONE-CONTAINING COMPOUND AND ITS USE IN 3D PRINTING BASF SE (DE) 2024-10-17 US disclosed
EP-4380990-A1 DUAL-CURE RESIN COMPOSITION COMPRISING URETDIONE-CONTAINING COMPOUND AND ITS USE IN 3D PRINTING BASF SE (DE) 2024-06-12 EP disclosed
CN-117980366-A One pot process for producing polycarbodiimide cured polymers 巴斯夫欧洲公司 2024-05-03 CN disclosed
WO-2023041443-A1 ONE-POT PROCESS FOR THE PRODUCTION OF POLYCARBODIIMIDE CURED POLYMERS BASF SE (DE) 2023-03-23 WO disclosed
WO-2023012000-A1 DUAL-CURE RESIN COMPOSITION COMPRISING URETDIONE-CONTAINING COMPOUND AND ITS USE IN 3D PRINTING BASF SE (DE) 2023-02-09 WO disclosed
US-11566145-B2 Polyurethane coating compositions and their use as gel coats COVESTRO LLC (US) 2023-01-31 US disclosed
CN-112384545-B Elastomeric polyurethane foams and process for producing the same 巴斯夫欧洲公司 2023-01-24 CN disclosed
US-20220340704-A1 SPRAY POLYURETHANE ELASTOMERS AND METHODS FOR PRODUCING THE SAME BASF SE (DE) 2022-10-27 US disclosed
US-6562932-B1 Optically clear, light-stable polyurethane-urea elastomer having an onset softening point of at least 130 degrees C., processed at ambient temperature and casted in a mold at an isocyanate index of 95 to 120. BAYER CORPORATION 2003-05-13 US disclosed
CN-1412214-A One-step method polyurethane-urea elastomer with light stability BAYER AG (US) 2003-04-23 CN disclosed
EP-1302491-A1 Light stable one-shot urethane-urea elastomers Bayer Corporation (US) 2003-04-16 EP disclosed
US-6530849-B2 Copolymer of toluene-2,4- or 2,6-diisocyanate, low molecular weight polyoxypropylene glycol and diamine functional chain extender; high resilience and shear resistance UNIROYAL CHEMICAL COMPANY, INC. 2003-03-11 US disclosed
WO-2002064658-A1 LOW COST, RESILIENT, SHEAR RESISTANT POLYURETHANE ELASTOMERS FOR GOLF BALL COVERS UNIROYAL CHEMICAL COMPANY, INC. (US) 2002-08-22 WO disclosed
US-20020049099-A1 Low cost, resilient, shear resistant polyurethane elastomers for golf ball covers UNIROYAL CHEMICAL COMPANY, INC. 2002-04-25 US disclosed
US-6309313-B1 AN INEXPENSIVE COVER OF A POLYETHERURETHANE COPOLYMER CHAIN EXTENDED BY A DIAMINE OR DIHYDROXY COMPOUND; POLYETHER MONOMER COMPRISING ETHYLENE GLYCOL OR ETHYLENE GLYCOL AND PROPYLENE GLYCOL; COLORFASTNESS; PHOTOSTABILITY UNIROYAL CHEMICAL COMPANY, INC. 2001-10-30 US disclosed
US-6174984-B1 Clear, resilient polyurethane elastomers UNIROYAL CHEMICAL COMPANY, INC. 2001-01-16 US disclosed
US-4631298-A REACTION INJECTION MOLDING POLYURETHANES ETHYL CORPORATION (US) 1986-12-23 US disclosed
US-4526905-A Chain extenders ETHYL CORPORATION (US) 1985-07-02 US disclosed