Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4339639 | 0.77 | ALDH1A1 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL12952456 | 0.71 | ALDH1A1 (0.45) | ALDH1A1TDP1MEN1RAB9AKMT2A | |
| SCHEMBL12216989 | 0.71 | ALDH1A1 (0.45) | ALDH1A1TDP1MEN1RAB9AKMT2A | |
| SCHEMBL7037424 | 0.70 | ALDH1A1 (0.39) | ALDH1A1TDP1MEN1RAB9AKMT2A | |
| SCHEMBL4110653 | 0.68 | ALDH1A1 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL4100352 | 0.68 | ALDH1A1 (0.33) | ALDH1A1TDP1LMNAHTTSMN1; SMN2 | |
| SCHEMBL4172895 | 0.68 | ALDH1A1 (0.33) | ALDH1A1TDP1LMNAHTTSMN1; SMN2 | |
| SCHEMBL11881351 | 0.67 | HSD17B10 (0.39) | ALDH1A1TDP1 | |
| SCHEMBL11584661 | 0.66 | ALDH1A1 (0.39) | ALDH1A1TDP1MEN1RAB9AKMT2A | |
| SCHEMBL12649671 | 0.65 | ALDH1A1 (0.43) | ALDH1A1TDP1MEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530688-B2 | Method for preparing exo-tricyclo[4.2.1.02,5]non-7-ene-3-spiro-1′-(3′-ethyl-3′-alumina)cyclopentane | Uchrezhdenie Rossiiskoi Akademii Nauk Institut Neftekhimii I Kataliza Ran (RU) | 2013-09-10 | — | — | US | claimed |
| US-20120184761-A1 | METHOD FOR PREPARING EXO-TRICYCLO[4.2.1.02.5]NON-7-ENE-3-SPIRO-1'-(3'- ETHYL- 3'-ALUMINA)CYCLOPENTANE | Uchrezhdenie Rossiiskoi Akademii Nauk Institut Neftekhimii I Kataliza Ran (RU) | 2012-07-19 | — | — | US | claimed |
| US-8530688-B2 | Method for preparing exo-tricyclo[4.2.1.02,5]non-7-ene-3-spiro-1′-(3′-ethyl-3′-alumina)cyclopentane | Uchrezhdenie Rossiiskoi Akademii Nauk Institut Neftekhimii I Kataliza Ran (RU) | 2013-09-10 | — | — | US | disclosed |
| US-8530688-B2 | Method for preparing exo-tricyclo[4.2.1.02,5]non-7-ene-3-spiro-1′-(3′-ethyl-3′-alumina)cyclopentane | Uchrezhdenie Rossiiskoi Akademii Nauk Institut Neftekhimii I Kataliza Ran (RU) | 2013-09-10 | — | — | US | disclosed |
| US-20120184761-A1 | METHOD FOR PREPARING EXO-TRICYCLO[4.2.1.02.5]NON-7-ENE-3-SPIRO-1'-(3'- ETHYL- 3'-ALUMINA)CYCLOPENTANE | Uchrezhdenie Rossiiskoi Akademii Nauk Institut Neftekhimii I Kataliza Ran (RU) | 2012-07-19 | — | — | US | disclosed |
| US-20120184761-A1 | METHOD FOR PREPARING EXO-TRICYCLO[4.2.1.02.5]NON-7-ENE-3-SPIRO-1'-(3'- ETHYL- 3'-ALUMINA)CYCLOPENTANE | Uchrezhdenie Rossiiskoi Akademii Nauk Institut Neftekhimii I Kataliza Ran (RU) | 2012-07-19 | — | — | US | disclosed |
| WO-2010134849-A1 | METHOD FOR PREPARING EXO-TRICYCLO[4.2.1.02.5]NON-7-ENE-3-SPIRO-1'-(3'- ETHYL-3'-ALUMINA)CYCLOPENTANE | УЧРЕЖДЕНИЕ РОССИЙСКОЙ АКАДЕМИИ НАУК ИНСТИТУТ НЕФТЕХИМИИ И КАТАЛИЗА РАН (RU) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184761-A1 | METHOD FOR PREPARING EXO-TRICYCLO[4.2.1.02.5]NON-7-ENE-3-SPIRO-1'-(3'- ETHYL- 3'-ALUMINA)CYCLOPENTANE | EXOC1, EXOC4, EXOC3 | ALDH1A1 2993/4885TDP1 1317/4885MEN1 1950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.