SCHEMBL4110653

SCHEMBL4110653

FC1=C(F)C2C3C=CC(C3)C2C1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12216989 0.68 ALDH1A1 (0.45) ALDH1A1TDP1
SCHEMBL12952456 0.68 ALDH1A1 (0.45) ALDH1A1TDP1
SCHEMBL3422940 0.68 ALDH1A1 (0.35) ALDH1A1TDP1
SCHEMBL7037424 0.67 ALDH1A1 (0.39) ALDH1A1TDP1
SCHEMBL4100352 0.65 ALDH1A1 (0.33) ALDH1A1TDP1
SCHEMBL4102173 0.65 ALDH1A1 (0.35) ALDH1A1TDP1
SCHEMBL4172895 0.65 ALDH1A1 (0.33) ALDH1A1TDP1
SCHEMBL11881351 0.64 HSD17B10 (0.39) ALDH1A1TDP1
SCHEMBL11584661 0.63 ALDH1A1 (0.39) ALDH1A1TDP1
SCHEMBL5349643 0.63 ALDH1A1 (0.31) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090209705-A1 THERMOPLASTIC RESIN COMPOSITION, OPTICAL FILM AND RETARDATION FILM JSR CORPORATION (JP) 2009-08-20 US disclosed
US-7449532-B2 Cycloolefin copolymer obtained by ring-opening polymerization, use thereof, and process for producing retardation plate comprising the copolymer JSR CORPORATION (JP) 2008-11-11 US disclosed
US-20070179264-A1 Copolymer of 8-methyl-8-methoxycarbonyltetracyclo[4.4.0.12,5.17,10]-3-dodecene or derivative with tricyclo[4.3.0.12,5]deca-3,7-diene or derivative; can be stretched even at low temperature around the glass transition temperature without causing cloudiness; excellent heat resistance and optical properties JSR CORPORATION (JP) 2007-08-02 US disclosed
EP-1795559-A1 THERMOPLASTIC RESIN COMPOSITION, OPTICAL FILM AND RETARDATION FILM JSR Corporation (JP) 2007-06-13 EP disclosed