Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 12/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621426 | 0.82 | ALDH1A1 (0.46) | KMOS1PR1 | |
| SCHEMBL9361798 | 0.79 | THRA (0.43) | S1PR1S1PR3 | |
| SCHEMBL9357514 | 0.79 | THRA (0.43) | S1PR1S1PR3 | |
| SCHEMBL9361624 | 0.79 | THRA (0.43) | S1PR1S1PR3 | |
| SCHEMBL5867386 | 0.79 | ALDH1A1 (0.53) | KMO | |
| SCHEMBL4622962 | 0.79 | S1PR1 (0.35) | KMOS1PR1 | |
| SCHEMBL566457 | 0.79 | ALDH1A1 (0.52) | KMOS1PR1S1PR3CSNK2A1RORC | |
| SCHEMBL15194032 | 0.78 | S1PR1 (0.52) | KMOS1PR1S1PR3 | |
| SCHEMBL3423534 | 0.78 | ALDH1A3 (0.62) | MAP4K4 | |
| SCHEMBL3427111 | 0.77 | MYC (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024783-A1 | BIARYLRHODANINE AND PYRIDYLRHODANINE COMPOUNDS AND THEIR USE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-03-04 | — | — | WO | disclosed |