Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MARS2 | Q96GW9 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187545 | 0.79 | TSHR (0.41) | HIF1AALDH1A1MEN1KMT2APOLB | |
| SCHEMBL2185729 | 0.72 | KMT2A (0.45) | HIF1AALDH1A1MEN1KMT2APOLB | |
| SCHEMBL10273422 | 0.72 | KMT2A (0.41) | HIF1AALDH1A1MEN1KMT2APOLB | |
| SCHEMBL15847208 | 0.70 | ADRA2A (0.38) | ATMADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL17247548 | 0.70 | ADRA2A (0.38) | ATMADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL30211545 | 0.70 | CA12 (0.46) | HIF1AMEN1KMT2APOLBATM | |
| SCHEMBL15973828 | 0.70 | ALDH1A1 (0.44) | HIF1AALDH1A1MEN1KMT2APOLB | |
| SCHEMBL15973830 | 0.70 | ALDH1A1 (0.44) | HIF1AALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3263969 | 0.69 | APOBEC3G (0.40) | HIF1AALDH1A1MEN1KMT2APOLB | |
| SCHEMBL10910583 | 0.69 | CA12 (0.39) | HIF1AALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220389487-A1 | Optical Instruments and Systems for Forensic DNA Quantitation | ANDE CORPORATION (US) | 2022-12-08 | — | — | US | disclosed |
| US-20220315996-A1 | Optical Instruments and Systems for Forensic DNA Quantitation | ANDE CORPORATION (US) | 2022-10-06 | — | — | US | disclosed |
| US-11441173-B2 | Optical instruments and systems for forensic DNA quantitation | ANDE CORPORATION (US) | 2022-09-13 | — | — | US | disclosed |
| EP-3587594-B1 | PARTICLE-ASSISTED NUCLEIC ACID SEQUENCING | HARVARD COLLEGE (US) | 2022-04-13 | — | — | EP | disclosed |
| US-20200248243-A1 | Methods for Forensic DNA Quantitation | ORBIMED ROYALTY & CREDIT OPPORTUNITIES IV, LP | 2020-08-06 | — | — | US | disclosed |
| US-10633701-B2 | Systems and methods for nucleic acid sequencing | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-04-28 | — | — | US | disclosed |
| US-10538804-B2 | Methods for forensic DNA quantitation | ANDE CORPORATION (US) | 2020-01-21 | — | — | US | disclosed |
| US-10457977-B2 | Particle-assisted nucleic acid sequencing | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-10-29 | — | — | US | disclosed |
| EP-3290531-B1 | PARTICLE-ASSISTED NUCLEIC ACID SEQUENCING | HARVARD COLLEGE (US) | 2019-07-24 | — | — | EP | disclosed |
| EP-1994182-B1 | DEGENERATE NUCLEOBASE ANALOGS | SIEMENS HEALTHCARE DIAGNOSTICS INC (US) | 2019-05-29 | — | — | EP | disclosed |
| US-20110267457-A1 | SYSTEMS AND METHODS FOR NUCLEIC ACID SEQUENCING | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2011-11-03 | — | — | US | disclosed |
| US-20110008785-A1 | METHODS FOR FORENSIC DNA QUANTITATION | NETBIO, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| US-20100055798-A1 | Degenerate Nucleobase Analogs | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2010-03-04 | — | — | US | disclosed |
| EP-1994182-A2 | DEGENERATE NUCLEOBASE ANALOGS | Siemens Healthcare Diagnostics Inc. (US) | 2008-11-26 | — | — | EP | disclosed |
| US-20070259827-A1 | Compositions and methods for enhancing discriminatory RNA interference | UNIVERSITY OF MASSACHUSETTS (US) | 2007-11-08 | — | — | US | disclosed |
| WO-2007106690-A2 | DEGENERATE NUCLEOBASE ANALOGS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2007-09-20 | — | — | WO | disclosed |
| WO-2007087451-A2 | COMPOSITIONS AND METHODS FOR ENHANCING DISCRIMINATORY RNA INTERFERENCE | UNIVERSITY OF MASSACHUSETTS (US) | 2007-08-02 | — | — | WO | disclosed |
| EP-1641942-A2 | COMBINATORIAL NUCLEOBASE OLIGOMERS COMPRISING UNIVERSAL BASE ANALOGUES AND METHODS FOR MAKING AND USING SAME | Applera Corporation (US) | 2006-04-05 | — | — | EP | disclosed |
| US-20050053979-A1 | Combinatorial nucleobase oligomers comprising universal base analogues and methods for making and using same | APPLIED BIOSYSTEMS, LLC | 2005-03-10 | — | — | US | disclosed |
| WO-2004111072-A2 | COMBINATORIAL NUCLEOBASE OLIGOMERS COMPRISING UNIVERSAL BASE ANALOGUES AND METHODS FOR MAKING AND USING SAME | APPLERA CORPORATION (US) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050053979-A1 | Combinatorial nucleobase oligomers comprising universal base analogues and methods for making and using same | DTYMK, UNG, TPR | HIF1A 4278/4885ALDH1A1 4255/4885MEN1 1869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.