Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.64 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.50 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | PPARA | Q07869 | 5/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10386196 | 1.00 | GPR84 (0.64) | GPR84ACE2FFAR1FFAR4PPARD | |
| SCHEMBL8049901 | 1.00 | GPR84 (0.64) | GPR84ACE2FFAR1FFAR4PPARD | |
| SCHEMBL951973 | 1.00 | GPR84 (0.64) | GPR84ACE2FFAR1FFAR4PPARD | |
| SCHEMBL5710467 | 1.00 | GPR84 (0.64) | GPR84ACE2FFAR1FFAR4PPARD | |
| SCHEMBL248934 | 1.00 | GPR84 (0.64) | GPR84ACE2FFAR1FFAR4PPARD | |
| SCHEMBL1234905 | 1.00 | GPR84 (0.64) | GPR84ACE2FFAR1FFAR4PPARD | |
| SCHEMBL23930717 | 1.00 | GPR84 (0.64) | GPR84ACE2FFAR1FFAR4PPARD | |
| SCHEMBL22612526 | 1.00 | GPR84 (0.64) | GPR84ACE2FFAR1FFAR4PPARD | |
| SCHEMBL22612511 | 1.00 | GPR84 (0.64) | GPR84ACE2FFAR1FFAR4PPARD | |
| SCHEMBL11940342 | 1.00 | GPR84 (0.64) | GPR84ACE2FFAR1FFAR4PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4524059-A | Fatty acid analogs | THE GENERAL HOSPITAL CORPORATION (US) | 1985-06-18 | — | — | US | claimed |
| US-8871179-B2 | Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid | THE GENERAL HOSPITAL CORPORATION (US) | 2014-10-28 | — | — | US | disclosed |
| US-20130052129-A1 | METHOD FOR MONITORING BLOOD FLOW AND METABOLIC UPTAKE IN TISSUE WITH RADIOLABELED ALKANOIC ACID | THE GENERAL HOSPITAL CORPORATION (US) | 2013-02-28 | — | — | US | disclosed |
| US-8309053-B2 | Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid | THE GENERAL HOSPITAL CORPORATION (US) | 2012-11-13 | — | — | US | disclosed |
| US-8268291-B2 | Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid | THE GENERAL HOSPITAL CORPORATION (US) | 2012-09-18 | — | — | US | disclosed |
| US-7790142-B2 | Using a radiolabeled fatty acid analog such as endo-[18F] fluoro- or [123I]iodo-3,4-cyclopropylheptadecanoic acid localized in tissue of interest, imaging, determining blood flow rate | THE GENERAL HOSPITAL CORPORATION (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090156848-A1 | METHOD FOR MONITORING BLOOD FLOW AND METABOLIC UPTAKE IN TISSUE WITH RADIOLABELED ALKANOIC ACID | THE GENERAL HOSPITAL CORPORATION (US) | 2009-06-18 | — | — | US | disclosed |
| US-7494642-B2 | Fatty acid derivatives; tissue-targeted therapy; tomography; cardiovascular disorders; liver disorders; kits | THE GENERAL HOSPITAL CORPORATION (US) | 2009-02-24 | — | — | US | disclosed |
| US-20080213178-A1 | Using a radiolabeled fatty acid analog such as endo-[18F] fluoro- or [123I]iodo-3,4-cyclopropylheptadecanoic acid localized in tissue of interest, imaging, determining blood flow rate | THE GENERAL HOSPITAL CORPORATION (US) | 2008-09-04 | — | — | US | disclosed |
| US-20080214853-A1 | Labeled cycloalkylidene-containing fatty acid analogs; tissue-targeted therapy; tomography; block the catabolic pathway, thus trapping these analogs in a virtually unmodified form in the tissues of interest such as heart or tumor | THE GENERAL HOSPITAL CORPORATION (US) | 2008-09-04 | — | — | US | disclosed |
| US-20080095702-A1 | Labeled fatty acid analogs; tissue-targeted therapy; tomography; block the catabolic pathway, thus trapping these analogs in a virtually unmodified form in the tissues of interest such as heart, liver, or tumor | THE GENERAL HOSPITAL CORPORATION (US) | 2008-04-24 | — | — | US | disclosed |
| EP-1786909-A1 | LIPID METABOLIC AND SIGNALLING PATHWAYS IN THE EPIDERMIS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2007-05-23 | — | — | EP | disclosed |
| EP-1622602-A4 | METHOD FOR MONITORING BLOOD FLOW AND METABOLIC UPTAKE IN TISSUE WITH RADIOLABELED ALKANOIC ACID | GEN HOSPITAL CORP (US) | 2006-06-21 | — | — | EP | disclosed |
| WO-2006015848-A1 | LIPID METABOLIC AND SIGNALLING PATHWAYS IN THE EPIDERMIS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2006-02-16 | — | — | WO | disclosed |
| EP-1626089-A1 | Lipid metabolic and signalling pathways in the epidermis | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2006-02-15 | — | — | EP | disclosed |
| EP-1622602-A2 | METHOD FOR MONITORING BLOOD FLOW AND METABOLIC UPTAKE IN TISSUE WITH RADIOLABELED ALKANOIC ACID | THE GENERAL HOSPITAL CORPORATION (US) | 2006-02-08 | — | — | EP | disclosed |
| US-20040253177-A1 | Fatty acid derivatives; tissue-targeted therapy; tomography; cardiovascular disorders; liver disorders; kits | GENERAL HOSPITAL CORPORATION, THE | 2004-12-16 | — | — | US | disclosed |
| WO-2004093650-A2 | METHOD FOR MONITORING BLOOD FLOW AND METABOLIC UPTAKE IN TISSUE WITH RADIOLABELED ALKANOIC ACID | THE GENERAL HOSPITAL CORPORATION (US) | 2004-11-04 | — | — | WO | disclosed |
| US-6066858-A | Autoradiographic process | FUJI PHOTO FILM CO., LTD. (JP) | 2000-05-23 | — | — | US | disclosed |
| US-4524059-A | Fatty acid analogs | THE GENERAL HOSPITAL CORPORATION (US) | 1985-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130052129-A1 | METHOD FOR MONITORING BLOOD FLOW AND METABOLIC UPTAKE IN TISSUE WITH RADIOLABELED ALKANOIC ACID | FABP3, FABP1, SLC27A2 | GPR84 267/4885ACE2 2060/4885FFAR1 10/4885 |
| US-20080214853-A1 | Labeled cycloalkylidene-containing fatty acid analogs; tissue-targeted therapy; tomography; block the catabolic pathway, thus trapping these analogs in a virtually unmodified form in the tissues of interest such as heart or tumor | FABP3, FFAR2, FFAR1 | GPR84 125/4885ACE2 1646/4885FFAR1 3/4885 |
| US-20080095702-A1 | Labeled fatty acid analogs; tissue-targeted therapy; tomography; block the catabolic pathway, thus trapping these analogs in a virtually unmodified form in the tissues of interest such as heart, liver, or tumor | FABP3, FABP1, FFAR2 | GPR84 143/4885ACE2 1967/4885FFAR1 4/4885 |
| US-20080213178-A1 | Using a radiolabeled fatty acid analog such as endo-[18F] fluoro- or [123I]iodo-3,4-cyclopropylheptadecanoic acid localized in tissue of interest, imaging, determining blood flow rate | FFAR3, FFAR2, FFAR1 | GPR84 144/4885ACE2 1983/4885FFAR1 3/4885 |
| US-20040253177-A1 | Fatty acid derivatives; tissue-targeted therapy; tomography; cardiovascular disorders; liver disorders; kits | FABP1, FABP3, FFAR2 | GPR84 138/4885ACE2 1098/4885FFAR1 5/4885 |
| US-20090156848-A1 | METHOD FOR MONITORING BLOOD FLOW AND METABOLIC UPTAKE IN TISSUE WITH RADIOLABELED ALKANOIC ACID | FABP3, FABP1, SLC27A2 | GPR84 267/4885ACE2 2060/4885FFAR1 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.