Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.64 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.50 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | PPARA | Q07869 | 5/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10386196 | 1.00 | GPR84 (0.64) | GPR84ACE2FFAR1FFAR4PPARD | |
| SCHEMBL8049901 | 1.00 | GPR84 (0.64) | GPR84ACE2FFAR1FFAR4PPARD | |
| SCHEMBL951973 | 1.00 | GPR84 (0.64) | GPR84ACE2FFAR1FFAR4PPARD | |
| SCHEMBL5710467 | 1.00 | GPR84 (0.64) | GPR84ACE2FFAR1FFAR4PPARD | |
| SCHEMBL248934 | 1.00 | GPR84 (0.64) | GPR84ACE2FFAR1FFAR4PPARD | |
| SCHEMBL1234905 | 1.00 | GPR84 (0.64) | GPR84ACE2FFAR1FFAR4PPARD | |
| SCHEMBL23930717 | 1.00 | GPR84 (0.64) | GPR84ACE2FFAR1FFAR4PPARD | |
| SCHEMBL3423500 | 1.00 | GPR84 (0.64) | GPR84ACE2FFAR1FFAR4PPARD | |
| SCHEMBL22612526 | 1.00 | GPR84 (0.64) | GPR84ACE2FFAR1FFAR4PPARD | |
| SCHEMBL22612511 | 1.00 | GPR84 (0.64) | GPR84ACE2FFAR1FFAR4PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116064442-A | Carbonyl reductase and application thereof in catalytic synthesis of (R) -beta-hydroxytetradecanoate methyl ester | 国蔷生物科技(南京)有限公司 | 2023-05-05 | — | — | CN | disclosed |
| US-20180028649-A1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS | INFECTIOUS DISEASE RESEARCH INSTITUTE (US) | 2018-02-01 | — | — | US | disclosed |
| US-9814772-B2 | Synthetic glucopyranosyl lipid adjuvants | INFECTIOUS DISEASE RESEARCH INSTITUTE (US) | 2017-11-14 | — | — | US | disclosed |
| US-20170182155-A1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS | INFECTIOUS DISEASE RES INST (US) | 2017-06-29 | — | — | US | disclosed |
| US-20170112924-A1 | SYNTHETIC DERIVATIVES OF MPL AND USES THEREOF | K2 HEALTHVENTURES LLC, AS CANADIAN COLLATERAL AGENT | 2017-04-27 | — | — | US | disclosed |
| US-9480740-B2 | Synthetic glucopyranosyl lipid adjuvants | INFECTIOUS DISEASE RESEARCH INSTITUTE (US) | 2016-11-01 | — | — | US | disclosed |
| US-20140356367-A1 | MONOPHOSPHORYLATED LIPID A DERIVATIVES | WAYNE STATE UNIVERSITY | 2014-12-04 | — | — | US | disclosed |
| US-20140328876-A1 | SYNTHETIC DERIVATIVES OF MPL AND USES THEREOF | VARIATION BIOTECHNOLOGIES INC. (CA) | 2014-11-06 | — | — | US | disclosed |
| US-20140322268-A1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS | INFECTIOUS DISEASE RESEARCH INSTITUTE (US) | 2014-10-30 | — | — | US | disclosed |
| US-8809285-B2 | Monophosphorylated lipid A derivatives | WAYNE STATE UNIVERSITY (US) | 2014-08-19 | — | — | US | disclosed |
| US-20120190633-A1 | MONOPHOSPHORYLATED LIPID A DERIVATIVES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140356367-A1 | MONOPHOSPHORYLATED LIPID A DERIVATIVES | SGMS1, PCYT1A, PHOSPHO1 | GPR84 1980/4885ACE2 3996/4885FFAR1 379/4885 |
| US-20120190633-A1 | MONOPHOSPHORYLATED LIPID A DERIVATIVES | SGMS1, PCYT1A, PHOSPHO1 | GPR84 1980/4885ACE2 3996/4885FFAR1 379/4885 |
| US-20140322268-A1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS | B3GAT3, GLA, LGALS8 | GPR84 1934/4885ACE2 1201/4885FFAR1 925/4885 |
| US-20140328876-A1 | SYNTHETIC DERIVATIVES OF MPL AND USES THEREOF | MPL, CD47, PLTP | GPR84 2777/4885ACE2 1972/4885FFAR1 3573/4885 |
| US-20180028649-A1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS | B3GAT3, GLA, LGALS8 | GPR84 2007/4885ACE2 1174/4885FFAR1 958/4885 |
| US-20170112924-A1 | SYNTHETIC DERIVATIVES OF MPL AND USES THEREOF | MPL, CD47, PLTP | GPR84 2876/4885ACE2 1833/4885FFAR1 3587/4885 |
| US-20170182155-A1 | SYNTHETIC GLUCOPYRANOSYL LIPID ADJUVANTS | B3GAT3, GLA, LGALS8 | GPR84 1934/4885ACE2 1201/4885FFAR1 925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.