Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8186531 | 0.79 | PRSS1 (0.52) | PRSS1PRSS2PRSS3EPHX2TSHR | |
| SCHEMBL9743495 | 0.78 | KMT2A (0.38) | PRSS1PRSS2PRSS3CA1CA2 | |
| SCHEMBL2489734 | 0.78 | ALDH1A1 (0.64) | PRSS1F2PLGPLAUPLAT | |
| SCHEMBL3417750 | 0.78 | CA1 (0.61) | PRSS1PRSS2PRSS3CA1CA2 | |
| SCHEMBL4603744 | 0.78 | LOXL2 (0.58) | PRSS1PRSS2PRSS3CA1CA2 | |
| SCHEMBL16280136 | 0.77 | PRSS1 (0.50) | PRSS1PRSS2PRSS3EPHX2TSHR | |
| SCHEMBL49984 | 0.77 | TSHR (0.63) | PRSS1PRSS2PRSS3TSHRCA1 | |
| Terephthalic Acid SCHEMBL28358133 | 0.77 | TSHR (0.63) | PRSS1PRSS2PRSS3TSHRCA1 | |
| Terephthalic Acid SCHEMBL28453225 | 0.77 | TSHR (0.63) | PRSS1PRSS2PRSS3TSHRCA1 | |
| SCHEMBL3424224 | 0.75 | PRSS1 (0.43) | PRSS1PRSS2PRSS3TSHRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2226637-A1 | Cross-linking agents on solid medium | Centre National de la Recherche Scientifique (CNRS) (FR) | 2010-09-08 | — | — | EP | disclosed |