SCHEMBL1225643

SCHEMBL1225643

Oc1ccc(-c2ccc3cc[nH]c3c2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.70
USP2 O75604 1/20 0.53
GAA P10253 1/20 0.53
ALOX15 P16050 1/20 0.53
RAD51 Q06609 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
FGFR1 P11362 2/20 0.53
FGFR2 P21802 2/20 0.53
FGFR3 P22607 2/20 0.53
ESR1 P03372 5/20 0.52
ESR2 Q92731 3/20 0.52
RIPK1 Q13546 1/20 0.50
BACE1 P56817 1/20 0.49
ENPP2 Q13822 2/20 0.48
NPC1 O15118 1/20 0.48
AHR P35869 3/20 0.48
CMA1 P23946 1/20 0.48
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL27298210 0.98 TYR (0.68) TYRUSP2GAAALOX15RAD51
Hydrochloric Acid SCHEMBL27297304 0.98 TYR (0.68) TYRUSP2GAAALOX15RAD51
SCHEMBL3334895 0.89 TYR (0.71) TYRUSP2GAAALOX15RAD51
SCHEMBL27500072 0.84 USP2 (0.70) TYRUSP2GAAALOX15RAD51
SCHEMBL29355861 0.83 TYR (1.00) TYRUSP2GAAALOX15RAD51
SCHEMBL34240 0.83 TYR (1.00) TYRUSP2GAAALOX15RAD51
SCHEMBL30253604 0.82 NPC1 (0.71) TYRFGFR1ENPP2NPC1AHR
SCHEMBL443799 0.82 NPC1 (0.71) TYRFGFR1ENPP2NPC1AHR
SCHEMBL147946 0.80 AHR (0.70) TYRESR1ENPP2NPC1AHR
SCHEMBL7085378 0.80 AHR (0.70) TYRESR1ENPP2NPC1AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1264498-C Primary intermediates for oxidative dyeing of hair PROCTER & GAMBLE (US) 2006-07-19 CN claimed
CN-1239467-C Primary intermediates for oxidative dyeing of hair P & G CLAIROL INC (US) 2006-02-01 CN claimed
CN-1229102-C Novel couplers for oxidative hair dyeing P & G CLAIROL INC (US) 2005-11-30 CN claimed
CN-1229100-C Primary intermediates for oxidative dyeing of hair P & G CLAIROL INC (US) 2005-11-30 CN claimed
CN-1219501-C Primary intermediates for oxidative dyeing of hair P & G CLAIROL INCORP (US) 2005-09-21 CN claimed
CN-1213722-C Couplers for oxidative hair dyeing P & G CLAIROL INC (US) 2005-08-10 CN claimed
CN-1198574-C Novel couplers for oxidative hair dyeing P & G CLAIROL INC (US) 2005-04-27 CN claimed
CN-1607935-A Primary intermediates for oxidative dyeing of hair PROCTER & GAMBLE (US) 2005-04-20 CN claimed
CN-1503657-A Novel couplers for oxidative hair dyeing P&G 2004-06-09 CN claimed
CN-1501792-A Novel couplers for oxidative hair dyeing P&G克莱罗尔公司 2004-06-02 CN claimed
CN-1487819-A Primary intermediates for oxidative dyeing of hair P&G 2004-04-07 CN claimed
CN-1486297-A Primary intermediates for oxidative dyeing of hair P&G 2004-03-31 CN claimed
CN-1486170-A Novel couplers for use in oxidative hair dyeing P&G 2004-03-31 CN claimed
CN-1486172-A Primary intermediates for oxidative dyeing of hair P&G 2004-03-31 CN claimed
CN-1486171-A Couplers for oxidative hair dyeing P&G克莱罗尔公司 2004-03-31 CN claimed
CN-1477947-A Primary intermediates for oxidative dyeing of hair P&G 2004-02-25 CN claimed
CN-1474679-A Novel couplers for oxidative hair dyeing P&G 2004-02-11 CN claimed
CN-1474681-A Novel couplers for oxidative hair dyeing P&G克莱罗尔公司 2004-02-11 CN claimed
CN-1474680-A Novel couplers for oxidative hair dyeing P&G克莱罗尔公司 2004-02-11 CN claimed
CN-1449276-A Primary intermediates for oxidative dyeing of hair P & G CLAIROL INC (US) 2003-10-15 CN claimed