SCHEMBL3424409

SCHEMBL3424409

Nc1ccc(-c2csc(-c3cccc(-c4nc(-c5ccc(N)cc5)cs4)c3)n2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 1/20 0.58
HSD17B2 P37059 1/20 0.58
SREBF2 Q12772 2/20 0.58
RAB9A P51151 5/20 0.54
KMT2A Q03164 4/20 0.54
MEN1 O00255 3/20 0.54
MAPT P10636 3/20 0.54
KDM4E B2RXH2 5/20 0.53
AR P10275 1/20 0.53
ALDH1A1 P00352 4/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
NPC1 O15118 2/20 0.51
LMNA P02545 2/20 0.51
NFKB1 P19838 1/20 0.51
NFKB2 Q00653 1/20 0.51
RELA Q04206 1/20 0.51
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
PKM P14618 1/20 0.50
HPGD P15428 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2220170 0.88 SREBF2 (0.70) SREBF2RAB9AKMT2AMEN1MAPT
SCHEMBL11152023 0.85 RAB9A (0.58) SREBF2RAB9AKMT2AMEN1MAPT
SCHEMBL12171986 0.84 KDM4E (0.64) HSD17B1HSD17B2SREBF2RAB9AKMT2A
SCHEMBL15774239 0.83 SREBF2 (0.55) HSD17B1HSD17B2SREBF2RAB9AKMT2A
SCHEMBL11146948 0.82 RAB9A (0.55) SREBF2RAB9AKMT2AMEN1MAPT
SCHEMBL14320817 0.81 RAB9A (0.77) RAB9AMAPTKDM4EALDH1A1NPC1
SCHEMBL4986233 0.79 KDM4E (0.73) SREBF2RAB9AKMT2AMEN1MAPT
SCHEMBL11212983 0.77 SREBF2 (0.82) SREBF2RAB9AKMT2AMEN1MAPT
SCHEMBL11213828 0.77 SREBF2 (0.82) SREBF2RAB9AKMT2AMEN1MAPT
SCHEMBL11215130 0.77 SREBF2 (0.82) SREBF2RAB9AKMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4526835-A Prepreg resin sheets formed by impregnating reinforcing substrate with curable polyimide, binding laminated sheets with heat, pressure HITACHI, LTD. (JP) 1985-07-02 US claimed
US-4486583-A MOLDING MATERIALS, COATINGS HITACHI, LTD. (JP) 1984-12-04 US claimed
US-4393188-A PRINTED CIRCUITS HITACHI CHEMICAL COMPANY, LTD. (JP) 1983-07-12 US claimed
US-4390596-A POLYAMINE, BIS-MALEIMIDE, FREE RADICAL CATALYST, FILLER RHONE-POULENC INDUSTRIES (FR) 1983-06-28 US claimed
US-4283522-A BY HEATING WITH A DIAMINE HITACHI CHEMICAL COMPANY, LTD. (JP) 1981-08-11 US claimed
US-4238591-A BIS-MALEIMIDE, SILANEDIOL OR SILOXANE RHONE-POULENC INDUSTRIES (FR) 1980-12-09 US claimed
US-4225498-A Preparation of N-substituted oligo-imides RHONE-POULENC INDUSTRIES (FR) 1980-09-30 US claimed
CN-113784999-B Fluorine-containing epoxy resin for electrical material and method for producing same 大金工业株式会社 2024-09-20 CN disclosed
US-11965060-B2 Fluorine-containing epoxy resin for electrical materials and method for manufacturing same DAIKIN INDUSTRIES, LTD. (JP) 2024-04-23 US disclosed
US-20220298294-A1 COMPOSITION, CURABLE COMPOSITION, AND CURED PRODUCT DAIKIN INDUSTRIES, LTD. (JP) 2022-09-22 US disclosed
EP-4053214-A1 COMPOSITION, CURABLE COMPOSITION, AND CURED PRODUCT Daikin Industries, Ltd. (JP) 2022-09-07 EP disclosed
CN-114829496-A Composition, curable composition, and cured product 大金工业株式会社 2022-07-29 CN disclosed
US-20220081507-A1 FLUORINE-CONTAINING EPOXY RESIN FOR ELECTRICAL MATERIALS AND METHOD FOR MANUFACTURING SAME DAIKIN INDUSTRIES, LTD. (JP) 2022-03-17 US disclosed
US-4057518-A Process for the manufacture of heat resistant multicellular materials RHONE-POULENC INDUSTRIES (FR) 1977-11-08 US disclosed
US-4013600-A STORAGE STABILITY RHONE-POULENC INDUSTRIES (FR) 1977-03-22 US disclosed
US-4012361-A Heat-stable polyimide resins from a bis-imide, a polyamine and an alazine RHONE-POULENC S.A. (FR) 1977-03-15 US disclosed
US-4010220-A AMINO COMPOUND, POLYURETHANE ELASTOMER RHONE-POULENC INDUSTRIES (FR) 1977-03-01 US disclosed
US-4005154-A Curing 1,2-epoxy with prepolymer based on polyamines and oligomers possessing imide groups RHONE-POULENC S.A. (FR) 1977-01-25 US disclosed
US-3998904-A POLYAMINES WITH IMIDE GROUPS RHONE-POULENC S.A. (FR) 1976-12-21 US disclosed
US-3933745-A Imide copolymers possessing hydroxyl groups RHONE-POULENC S.A. (FR) 1976-01-20 US disclosed