Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SREBF2 | Q12772 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | AR | P10275 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 8/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11215130 | 0.91 | SREBF2 (0.82) | SREBF2KDM4EKMT2AARRAB9A | |
| SCHEMBL11213828 | 0.91 | SREBF2 (0.82) | SREBF2KDM4EKMT2AARRAB9A | |
| SCHEMBL11212983 | 0.91 | SREBF2 (0.82) | SREBF2KDM4EKMT2AARRAB9A | |
| SCHEMBL11464717 | 0.89 | SREBF2 (0.79) | SREBF2KDM4EKMT2AARRAB9A | |
| SCHEMBL2781370 | 0.89 | KDM4E (0.85) | SREBF2KDM4EKMT2AARRAB9A | |
| SCHEMBL3424409 | 0.88 | HSD17B1 (0.58) | SREBF2KDM4EKMT2AARRAB9A | |
| SCHEMBL11146948 | 0.87 | RAB9A (0.55) | SREBF2KDM4EKMT2AARRAB9A | |
| SCHEMBL11152023 | 0.87 | RAB9A (0.58) | SREBF2KDM4EKMT2AARRAB9A | |
| SCHEMBL15774239 | 0.84 | SREBF2 (0.55) | SREBF2KDM4EKMT2AARRAB9A | |
| SCHEMBL4986233 | 0.84 | KDM4E (0.73) | SREBF2KDM4EKMT2AARRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829496-A | Composition, curable composition, and cured product | 大金工业株式会社 | 2022-07-29 | — | — | CN | disclosed |
| CN-113784999-A | Fluorine-containing epoxy resin for electrical material and method for producing same | 大金工业株式会社 | 2021-12-10 | — | — | CN | disclosed |
| WO-2021117486-A1 | COMPOSITION, CURABLE COMPOSITION, AND CURED PRODUCT | ダイキン工業株式会社 | 2021-06-17 | — | — | WO | disclosed |
| US-9174949-B2 | Hedgehog inhibitors | SELEXAGEN THERAPEUTICS, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-9174949-B2 | Hedgehog inhibitors | SELEXAGEN THERAPEUTICS, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-9174949-B2 | Hedgehog inhibitors | SELEXAGEN THERAPEUTICS, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| CN-103113582-A | Polyamide acid and polyphenyl-oxazine ketone imide containing biphenyl structure and preparation method thereof | UNIV HARBIN ENG | 2013-05-22 | — | — | CN | disclosed |
| US-20130012513-A1 | HEDGEHOG INHIBITORS | SELEXAGEN THERAPEUTICS, INC. | 2013-01-10 | — | — | US | disclosed |
| US-20130012513-A1 | HEDGEHOG INHIBITORS | SELEXAGEN THERAPEUTICS, INC. | 2013-01-10 | — | — | US | disclosed |
| US-20130012513-A1 | HEDGEHOG INHIBITORS | SELEXAGEN THERAPEUTICS, INC. | 2013-01-10 | — | — | US | disclosed |
| EP-2521451-A1 | HEDGEHOG INHIBITORS | Selexagen Therapeutics, Inc. (US) | 2012-11-14 | — | — | EP | disclosed |
| WO-2011085128-A1 | HEDGEHOG INHIBITORS | SELEXAGEN THERAPEUTICS, INC. (US) | 2011-07-14 | — | — | WO | disclosed |
| WO-2011085128-A1 | HEDGEHOG INHIBITORS | SELEXAGEN THERAPEUTICS, INC. (US) | 2011-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012513-A1 | HEDGEHOG INHIBITORS | SHH, SMO, GLI1 | SREBF2 1221/4885KDM4E 2019/4885KMT2A 2623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.