Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SREBF2 | Q12772 | 2/20 | 0.53 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.51 |
| ▸ | ATP4A | P20648 | 2/20 | 0.50 |
| ▸ | ATP4B | P51164 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11152023 | 0.88 | RAB9A (0.58) | RAB9AALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL2220170 | 0.87 | SREBF2 (0.70) | RAB9AALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL3424409 | 0.82 | HSD17B1 (0.58) | RAB9AALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL1206446 | 0.80 | ALDH1A1 (0.61) | RAB9AALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL4986233 | 0.79 | KDM4E (0.73) | RAB9AALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL1821128 | 0.78 | ALDH1A1 (0.54) | RAB9AALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL172279 | 0.78 | ALDH1A1 (0.70) | RAB9AALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL11765529 | 0.78 | RAB9A (0.58) | RAB9AALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL14320817 | 0.77 | RAB9A (0.77) | RAB9AALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL11213828 | 0.76 | SREBF2 (0.82) | RAB9AALDH1A1KDM4ENPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4390596-A | POLYAMINE, BIS-MALEIMIDE, FREE RADICAL CATALYST, FILLER | RHONE-POULENC INDUSTRIES (FR) | 1983-06-28 | — | — | US | claimed |
| US-4238591-A | BIS-MALEIMIDE, SILANEDIOL OR SILOXANE | RHONE-POULENC INDUSTRIES (FR) | 1980-12-09 | — | — | US | claimed |
| US-4225498-A | Preparation of N-substituted oligo-imides | RHONE-POULENC INDUSTRIES (FR) | 1980-09-30 | — | — | US | claimed |
| US-4390596-A | POLYAMINE, BIS-MALEIMIDE, FREE RADICAL CATALYST, FILLER | RHONE-POULENC INDUSTRIES (FR) | 1983-06-28 | — | — | US | disclosed |
| US-4361690-A | STRONG, DIELECTRIC THERMOSETTING RESINS | RHONE-POULENC INDUSTRIES (FR) | 1982-11-30 | — | — | US | disclosed |
| US-4299946-A | THERMOSETTING RESINS | RHONE-POULENC INDUSTRIES (FR) | 1981-11-10 | — | — | US | disclosed |
| US-4275184-A | HYDROSILATION OF POLYDIMETHYL SILOXANE | RHONE-POULENC INDUSTRIES (FR) | 1981-06-23 | — | — | US | disclosed |
| US-4238591-A | BIS-MALEIMIDE, SILANEDIOL OR SILOXANE | RHONE-POULENC INDUSTRIES (FR) | 1980-12-09 | — | — | US | disclosed |
| US-4225498-A | Preparation of N-substituted oligo-imides | RHONE-POULENC INDUSTRIES (FR) | 1980-09-30 | — | — | US | disclosed |
| US-4225497-A | ACID CATALYSTS FOR IMIDATION | RHONE-POULENC INDUSTRIES (FR) | 1980-09-30 | — | — | US | disclosed |
| US-4213914-A | ADDITION-CONDENSATION COPOLYMERS | RHONE-POULENC INDUSTRIES (FR) | 1980-07-22 | — | — | US | disclosed |
| US-4147711-A | Ethylenic silicon compounds and thermoplastic elastomers obtained therefrom | RHONE-POULENC INDUSTRIES (FR) | 1979-04-03 | — | — | US | disclosed |
| US-4088670-A | P-(DIMETHYLVINYLSILYL-METHOXY)-BENZOYL CHLORIDE FROM DIMETHYLVINYL-CHLOROMETHYLSILANE AND A P-HYDROXYBENZOIC ACID | RHONE-POULENC INDUSTRIES (FR) | 1978-05-09 | — | — | US | disclosed |
| US-4064192-A | Heat-stable polyimide resins | RHONE-POULENC S.A. (FR) | 1977-12-20 | — | — | US | disclosed |
| US-4012361-A | Heat-stable polyimide resins from a bis-imide, a polyamine and an alazine | RHONE-POULENC S.A. (FR) | 1977-03-15 | — | — | US | disclosed |
| US-4010220-A | AMINO COMPOUND, POLYURETHANE ELASTOMER | RHONE-POULENC INDUSTRIES (FR) | 1977-03-01 | — | — | US | disclosed |