Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 4/20 | 0.32 |
| ▸ | CTSB | P07858 | 4/20 | 0.32 |
| ▸ | CTSS | P25774 | 4/20 | 0.32 |
| ▸ | CTSK | P43235 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1812604 | 0.78 | MAPT (0.37) | PLAUPLATMEN1KMT2AMAPT | |
| SCHEMBL342456 | 0.77 | PPARD (0.36) | PLAUPLATMAPTPOLBSMN1; SMN2 | |
| SCHEMBL3757633 | 0.77 | SMN1; SMN2 (0.37) | PLAUPLATMEN1KMT2ANPC1 | |
| SCHEMBL3164180 | 0.74 | SMN1; SMN2 (0.34) | PLAUPLATMEN1KMT2AMAPT | |
| SCHEMBL1153521 | 0.74 | LPAR1 (0.36) | PLAUPLATMEN1KMT2AMAPT | |
| SCHEMBL10267549 | 0.72 | FFAR4 (0.33) | MEN1KMT2ANPC1MAPTXBP1 | |
| SCHEMBL2433657 | 0.72 | L3MBTL1 (0.35) | PLAUPLATMEN1KMT2AMAPT | |
| SCHEMBL7711506 | 0.71 | KMT2A (0.44) | MEN1KMT2ANPC1MAPTXBP1 | |
| SCHEMBL6290175 | 0.71 | P2RX7 (0.35) | MEN1KMT2APOLBDGAT2BDKRB1 | |
| SCHEMBL7872058 | 0.71 | P2RX7 (0.40) | SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507537-B2 | Trifluromethoxyphenyl-substituted tetramic acid derivatives pesticides and/or herbicides | BAYER CROPSCIENCE AG (DE) | 2013-08-13 | — | — | US | disclosed |
| US-8507537-B2 | Trifluromethoxyphenyl-substituted tetramic acid derivatives pesticides and/or herbicides | BAYER CROPSCIENCE AG (DE) | 2013-08-13 | — | — | US | disclosed |
| US-20120015807-A1 | Trifluromethoxyphenyl-Substituted Tetramic Acid Derivatives Pesticides and/or Herbicides | BAYER CROPSCIENCE AG (DE) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015807-A1 | Trifluromethoxyphenyl-Substituted Tetramic Acid Derivatives Pesticides and/or Herbicides | DDT, PTPRG, SLC1A5 | PLAU 4227/4885PLAT 2624/4885MEN1 4062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.