Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 11/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | ACACA | Q13085 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3732990 | 0.86 | P2RX7 (0.35) | P2RX7 | |
| SCHEMBL12460527 | 0.83 | MAPT (0.32) | P2RX7 | |
| SCHEMBL2525179 | 0.82 | P2RX7 (0.32) | P2RX7MEN1KMT2APOLBOPRM1 | |
| SCHEMBL7872058 | 0.81 | P2RX7 (0.40) | P2RX7ABCB1 | |
| SCHEMBL2947752 | 0.80 | EPHX2 (0.34) | P2RX7 | |
| SCHEMBL20021197 | 0.79 | P2RX7 (0.33) | P2RX7MEN1KMT2A | |
| SCHEMBL4501235 | 0.78 | MEN1 (0.33) | P2RX7MEN1KMT2APOLB | |
| SCHEMBL13039907 | 0.78 | P2RX7 (0.35) | P2RX7 | |
| SCHEMBL6290176 | 0.77 | MEN1 (0.35) | MEN1KMT2AACACBACACAPOLB | |
| SCHEMBL12382100 | 0.77 | MEN1 (0.34) | P2RX7MEN1KMT2AOPRM1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6861391-B1 | Trifluoromethyl-substituted spirocyclic ketoenols | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-01 | — | — | US | disclosed |