Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.36 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13252246 | 0.85 | ALDH1A1 (0.44) | POLBSMN1; SMN2TSHRL3MBTL1MEN1 | |
| SCHEMBL3425238 | 0.85 | ALDH1A1 (0.44) | POLBSMN1; SMN2TSHRL3MBTL1MEN1 | |
| SCHEMBL3425803 | 0.81 | L3MBTL1 (0.38) | POLBCYP2D6TSHRL3MBTL1MEN1 | |
| SCHEMBL3428912 | 0.80 | MEN1 (0.60) | POLBSMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL1347628 | 0.79 | POLB (0.66) | POLBCYP2D6SMN1; SMN2TSHRPHLPP2 | |
| SCHEMBL1347624 | 0.79 | POLB (0.66) | POLBCYP2D6SMN1; SMN2TSHRPHLPP2 | |
| SCHEMBL14497459 | 0.78 | POLB (0.51) | POLBCYP2D6SMN1; SMN2TSHRPHLPP2 | |
| SCHEMBL3423117 | 0.78 | L3MBTL1 (0.36) | SMN1; SMN2TSHRL3MBTL1ALDH1A1KEAP1 | |
| SCHEMBL31742273 | 0.77 | POLB (0.54) | POLBCYP2D6TSHRPHLPP2MEN1 | |
| SCHEMBL408153 | 0.73 | POLB (1.00) | POLBCYP2D6SMN1; SMN2TSHRPHLPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754273-B2 | Method of printing a time-temperature indicator based on azo coupling reactions onto a susbtrate | CIBA SPECIALTY CHEMICALS CORP. (US) | 2010-07-13 | — | — | US | disclosed |
| US-20070218206-A1 | Method of Printing a Time-Temperature Indicator Based on Azo Coupling Reactions onto a Susbtrate | CIBA SPECIALTY CHEMICALS CORP. | 2007-09-20 | — | — | US | disclosed |