Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14497015 | 0.81 | NPC1 (0.44) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL31742273 | 0.81 | POLB (0.54) | POLBCYP2D6PHLPP2RPS6KA3MAPT | |
| SCHEMBL13252239 | 0.80 | ALDH1A1 (0.41) | POLBLMNAMAPTALDH1A1KDM4E | |
| SCHEMBL14438172 | 0.80 | CES2 (0.39) | POLBCYP2D6MAPTALDH1A1KDM4E | |
| SCHEMBL14497142 | 0.79 | POLB (0.47) | POLBCYP2D6PHLPP2LMNARPS6KA3 | |
| SCHEMBL2938133 | 0.79 | LMNA (0.68) | POLBCYP2D6PHLPP2LMNARPS6KA3 | |
| SCHEMBL2938128 | 0.79 | LMNA (0.68) | POLBCYP2D6PHLPP2LMNARPS6KA3 | |
| SCHEMBL3425142 | 0.78 | POLB (0.55) | POLBCYP2D6PHLPP2LMNARPS6KA3 | |
| SCHEMBL14497451 | 0.78 | MAPT (0.54) | POLBLMNAMAPTALDH1A1KDM4E | |
| SCHEMBL14497439 | 0.78 | MAPT (0.57) | POLBLMNAMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229479-B2 | Method of coloring porous material | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-06-12 | — | — | US | disclosed |