SCHEMBL342544

SCHEMBL342544

[CH](C1CCCO1)C1CCCO1

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9450020 0.94 NOS2 (0.31) NOS2
SCHEMBL863535 0.91
SCHEMBL28441198 0.80
SCHEMBL3298616 0.79
SCHEMBL14178843 0.77
SCHEMBL8014507 0.77
SCHEMBL19462726 0.77
SCHEMBL12060984 0.77
SCHEMBL7002635 0.77
SCHEMBL230949 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 599 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108368098-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-01-28 CN claimed
US-11186596-B2 Anticancer indenes, indanes, azaindenes, azaindanes, pharmaceutical compositions and uses ADT PHARMACEUTICALS, LLC (US) 2021-11-30 US claimed
WO-2021105101-A1 [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACID DERIVATIVES AND SALTS THEREOF, CROP PROTECTION COMPOSITIONS COMPRISING THEM, METHODS FOR PRODUCING THEM AND USE THEREOF AS SAFENERS BAYER AKTIENGESELLSCHAFT (DE) 2021-06-03 WO claimed
US-10975054-B2 Indenyl compounds, pharmaceutical compositions, and medical uses thereof ADT PHARMACEUTICALS, LLC (US) 2021-04-13 US claimed
EP-3784228-A1 ANTICANCER INDENES, INDANES, AZAINDENES, AZAINDANES, PHARMACEUTICAL COMPOSITIONS AND USES ADT Pharmaceuticals, LLC (US) 2021-03-03 EP claimed
CN-112020354-A Anti-cancer indenes, indanes, aza-indenes, aza-indanes, pharmaceutical compositions and uses ADT制药有限责任公司 2020-12-01 CN claimed
US-20200048217-A1 INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF ADT PHARMACEUTICALS, LLC (US) 2020-02-13 US claimed
EP-3390398-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES Syngenta Participations AG (CH) 2018-10-24 EP claimed
WO-2017103223-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2017-06-22 WO claimed
EP-2598484-B1 PROCESS FOR THE PREPARATION OF KEY INTERMEDIATES FOR THE SYNTHESIS OF STATINS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF LEK PHARMACEUTICALS (SI) 2016-06-29 EP claimed
EP-0355544-A2 Substituted decalin amines, method for their preparation and their use in pesticides BAYER AG (DE) 1990-02-28 EP claimed
EP-0355597-A1 Substituted dioxolanylethylamines, process for their preparation, their use in pesticides, and intermediates BAYER AG (DE) 1990-02-28 EP claimed
EP-0356158-A1 Aminopyrimidine derivative, process for preparing the derivative, and insecticide or bactericide containing the derivative UBE INDUSTRIES, LTD. (JP) 1990-02-28 EP claimed
US-4851405-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1989-07-25 US claimed
US-4800202-A FUNGICIDES, PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1989-01-24 US claimed
EP-0289913-A2 Parasiticidal agent based on substituted aminomethyl heterocycles BAYER AG (DE) 1988-11-09 EP claimed
EP-0281842-A1 Aminomethyl-heterocycles BAYER AG (DE) 1988-09-14 EP claimed
EP-0278352-A2 Aminomethyl-tetrahydro-furanes BAYER AG (DE) 1988-08-17 EP claimed
EP-0157876-A1 HERBICIDAL 1-ARYL-$g(D)?2 -1,2,4-TRIAZOLIN-5-ONES FMC Corporation (US) 1985-10-16 EP claimed
WO-1985001637-A1 HERBICIDAL 1-ARYL-DELTA2-1,2,4-TRIAZOLIN-5-ONES FMC CORPORATION (US) 1985-04-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200048217-A1 INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF INSRR, INSR, BRCA1 NOS2 889/4885
US-11186596-B2 Anticancer indenes, indanes, azaindenes, azaindanes, pharmaceutical compositions and uses CCNA2, CDKN1A, CCNA1 NOS2 210/4885
US-10975054-B2 Indenyl compounds, pharmaceutical compositions, and medical uses thereof INSRR, INSR, BRCA1 NOS2 889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.