SCHEMBL3425510

SCHEMBL3425510

COc1ccc(N=NNCC(=O)O)c(S(=O)(=O)O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.50
POLB P06746 1/20 0.42
GAA P10253 1/20 0.42
TSHR P16473 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.40
LMNA P02545 1/20 0.37
MPL P40238 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PTGS1 P23219 1/20 0.36
AKR1C3 P42330 1/20 0.36
AKR1C2 P52895 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HIF1A Q16665 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
PAX8 Q06710 1/20 0.36
KLF5 Q13887 1/20 0.36
ALDH1A1 P00352 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3425746 0.85 MAPT (0.38) MAPTPOLBGAATSHRL3MBTL1
SCHEMBL3428032 0.84 SLC2A1 (0.37) MAPTGAAL3MBTL1MPLMEN1
SCHEMBL3423466 0.82 P2RX5 (0.38) MAPTPOLBGAAHSD17B10MEN1
SCHEMBL3426212 0.77 CA1 (0.37) POLBGAATSHR
SCHEMBL12052698 0.77 MPL (0.42) MAPTL3MBTL1MPLHSD17B10MEN1
SCHEMBL14496931 0.77 MAPT (0.41) MAPTPOLBGAATSHRL3MBTL1
SCHEMBL13252176 0.77 MAPT (0.41) MAPTPOLBGAATSHRL3MBTL1
SCHEMBL3425394 0.73 CYP1A2 (0.52) MAPTPOLBMPLMEN1KMT2A
SCHEMBL10488378 0.72 L3MBTL1 (0.41) MAPTGAAL3MBTL1MPLHSD17B10
SCHEMBL10488382 0.72 L3MBTL1 (0.41) MAPTL3MBTL1MPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7754273-B2 Method of printing a time-temperature indicator based on azo coupling reactions onto a susbtrate CIBA SPECIALTY CHEMICALS CORP. (US) 2010-07-13 US disclosed
US-20070218206-A1 Method of Printing a Time-Temperature Indicator Based on Azo Coupling Reactions onto a Susbtrate CIBA SPECIALTY CHEMICALS CORP. 2007-09-20 US disclosed
EP-1779104-A1 METHOD OF PRINTING A TIME-TEMPERATURE INDICATOR BASED ON AZO COUPLING REACTIONS ONTO A SUBSTRATE Ciba SC Holding AG (CH) 2007-05-02 EP disclosed
WO-2006015962-A1 METHOD OF PRINTING A TIME-TEMPERATURE INDICATOR BASED ON AZO COUPLING REACTIONS ONTO A SUBSTRATE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-02-16 WO disclosed