Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375735 | 0.90 | LMNA (0.57) | LMNAKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL11169691 | 0.85 | NPC1 (0.53) | LMNAKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9013500 | 0.85 | LMNA (0.68) | LMNAKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL1772953 | 0.84 | LMNA (1.00) | LMNAKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL17412398 | 0.84 | MEN1 (0.55) | LMNAKMT2AMEN1PTGS2NR1H4 | |
| SCHEMBL11513769 | 0.82 | LMNA (0.70) | LMNAKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL28330431 | 0.82 | LMNA (0.64) | LMNAKMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL632828 | 0.82 | LMNA (0.64) | LMNAKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8031410 | 0.80 | LMNA (0.62) | LMNAKMT2ANPC1RAB9AMAPT | |
| SCHEMBL5487045 | 0.79 | LMNA (0.71) | LMNAKMT2ANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7731985-B2 | 4-aminopyrimidines and their use for the antimicrobial treatment of surfaces | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-06-08 | — | — | US | disclosed |
| EP-1484971-B1 | USE OF 4-AMINOPYRIMIDINES FOR THE ANTIMICROBIAL TREATMENT OF SURFACES | CIBA SC HOLDING AG (CH) | 2007-07-04 | — | — | EP | disclosed |
| US-20050143387-A1 | 4-Aminopyrimidines and their use for the antimicrobial treatment of surfaces | CIBA SPECIALTY CHEMICALS CORP. | 2005-06-30 | — | — | US | disclosed |
| EP-1484971-A1 | 4-AMINOPYRIMIDINES AND THEIR USE FOR THE ANTIMICROBIAL TREATMENT OF SURFACES | Ciba SC Holding AG (CH) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003077656-A1 | 4-AMINOPYRIMIDINES AND THEIR USE FOR THE ANTIMICROBIAL TREATMENT OF SURFACES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-09-25 | — | — | WO | disclosed |
| EP-0031796-B1 | 4-HETEROCYCLYL-4'-VINYL-STILBENES | CIBA-GEIGY AG (CH) | 1985-01-23 | — | — | EP | disclosed |
| EP-0020298-B1 | BENZOXAZOLYL STILBENES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS OPTICAL BRIGHTENERS FOR ORGANIC MATERIALS | CIBA-GEIGY AG (CH) | 1983-06-22 | — | — | EP | disclosed |
| US-4366189-A | WHITENERS | CIBA-GEIGY CORPORATION (US) | 1982-12-28 | — | — | US | disclosed |
| US-4297234-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1981-10-27 | — | — | US | disclosed |
| EP-0031796-A2 | 4-Heterocyclyl-4'-vinyl-stilbenes | CIBA-GEIGY AG (CH) | 1981-07-08 | — | — | EP | disclosed |
| EP-0020298-A1 | Benzoxazolyl stilbenes, process for their preparation and their use as optical brighteners for organic materials | CIBA-GEIGY AG (CH) | 1980-12-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143387-A1 | 4-Aminopyrimidines and their use for the antimicrobial treatment of surfaces | DPM1, UNG, DPYD | LMNA 4211/4885KMT2A 3109/4885NPC1 4111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.