Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3450860 | 0.86 | LMNA (0.47) | LMNAADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL3425538 | 0.85 | LMNA (0.72) | LMNAADORA2AADORA3NPC1RAB9A | |
| SCHEMBL1772953 | 0.81 | LMNA (1.00) | LMNAADORA2AADORA1NPC1RAB9A | |
| SCHEMBL8031410 | 0.81 | LMNA (0.62) | LMNAADORA3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11513769 | 0.79 | LMNA (0.70) | LMNANPC1RAB9AKMT2AMAPT | |
| SCHEMBL28330431 | 0.79 | LMNA (0.64) | LMNANPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL632828 | 0.79 | LMNA (0.64) | LMNANPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL28859110 | 0.78 | ADORA2A (0.47) | LMNAADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL9013731 | 0.78 | NPC1 (0.47) | LMNAADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL5749149 | 0.76 | LMNA (0.61) | LMNANPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589477-A | LEARNING ENHANCEMENT, CNS | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0555478-A1 | PYRIMIDINE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-18 | — | — | EP | disclosed |