Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 12/20 | 0.55 |
| ▸ | DDO | Q99489 | 5/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361211 | 0.81 | DAO (0.53) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3360159 | 0.78 | DAO (0.58) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3421760 | 0.75 | DAO (0.55) | DAODDOPGR | |
| SCHEMBL9390027 | 0.75 | DAO (0.68) | DAODDOPGRALDH1A1LMNA | |
| SCHEMBL9389013 | 0.74 | DAO (0.58) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3425229 | 0.74 | DAO (0.57) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL17503338 | 0.73 | GRIN2D (0.52) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3360150 | 0.72 | DAO (0.59) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL8328414 | 0.72 | GLA (0.43) | ALDH1A1 | |
| SCHEMBL16767845 | 0.71 | DAO (1.00) | DAODDOALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |