Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 14/20 | 0.53 |
| ▸ | DDO | Q99489 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3425539 | 0.81 | DAO (0.55) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3360159 | 0.80 | DAO (0.58) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL7784347 | 0.76 | DAO (0.46) | DAODDOMAPTGRIN2DGRIN3B | |
| SCHEMBL3360150 | 0.75 | DAO (0.59) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9093987 | 0.74 | DAO (0.49) | DAODDO | |
| SCHEMBL3433397 | 0.73 | DAO (0.67) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3424908 | 0.73 | DAO (0.53) | DAODDO | |
| SCHEMBL3360987 | 0.73 | DAO (0.61) | DAODDOMAPT | |
| SCHEMBL8583717 | 0.73 | DAO (0.66) | DAODDOMAPT | |
| SCHEMBL3418547 | 0.73 | DAO (0.61) | DAODDOMAPTGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |