Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 13/20 | 0.55 |
| ▸ | DDO | Q99489 | 7/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362656 | 0.85 | DAO (0.61) | DAODDOPGR | |
| SCHEMBL3424908 | 0.81 | DAO (0.53) | DAODDONEK1 | |
| SCHEMBL3360159 | 0.78 | DAO (0.58) | DAODDOPGR | |
| SCHEMBL22408139 | 0.77 | KEAP1 (0.34) | DAODDO | |
| SCHEMBL3425539 | 0.75 | DAO (0.55) | DAODDOPGR | |
| SCHEMBL22394993 | 0.75 | IDO1 (0.61) | — | |
| SCHEMBL29425167 | 0.75 | IDO1 (0.61) | — | |
| SCHEMBL3424009 | 0.74 | DAO (0.57) | DAODDO | |
| SCHEMBL3360150 | 0.72 | DAO (0.59) | DAODDO | |
| SCHEMBL3420842 | 0.72 | DAO (0.38) | DAODDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |