SCHEMBL24577342

SCHEMBL24577342

Cc1ccccc1-c1nc(Cl)cc(-c2ccccc2)n1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.53
HSP90AA1 P07900 1/20 0.53
HSP90AB1 P08238 1/20 0.53
LMNA P02545 1/20 0.53
KMT2A Q03164 7/20 0.47
MEN1 O00255 6/20 0.47
ALDH1A1 P00352 4/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
HPGD P15428 3/20 0.47
MAPT P10636 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
RAB9A P51151 3/20 0.45
POLB P06746 1/20 0.45
PKM P14618 1/20 0.45
CYP1A2 P05177 3/20 0.44
CYP2C19 P33261 3/20 0.44
NPC1 O15118 2/20 0.44
ENPP3 O14638 1/20 0.44
ENPP1 P22413 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18731826 0.88 MEN1 (0.52) KDM4ELMNAKMT2AMEN1ALDH1A1
SCHEMBL15840233 0.87 LMNA (0.62) KDM4EHSP90AA1HSP90AB1LMNAKMT2A
SCHEMBL11286099 0.86 KMT2A (0.56) KDM4EHSP90AA1LMNAKMT2AMEN1
SCHEMBL31643196 0.84 KDM4E (0.58) KDM4EHSP90AA1HSP90AB1LMNAKMT2A
SCHEMBL20174193 0.84 MEN1 (0.51) KDM4EKMT2AMEN1ALDH1A1L3MBTL1
SCHEMBL3425870 0.81 KMT2A (0.70) KDM4EHSP90AA1LMNAKMT2AMEN1
SCHEMBL5191469 0.80 HSP90AA1 (0.62) KDM4EHSP90AA1HSP90AB1LMNAKMT2A
SCHEMBL20174196 0.80 NR1H4 (0.48) KDM4ELMNAKMT2AMEN1ALDH1A1
SCHEMBL423874 0.80 KDM4E (0.66) KDM4EHSP90AA1HSP90AB1LMNAKMT2A
SCHEMBL29750648 0.79 KDM4E (0.51) KDM4EHSP90AA1HSP90AB1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022139360-A1 ORGANIC LIGHT-EMITTING COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 솔루스첨단소재 주식회사 2022-06-30 WO disclosed