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Beclomethasone Dipropionate

Beclomethasone Dipropionate

SCHEMBL3425925

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nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

NR3C1

The experimentally established mechanism targets of Beclomethasone Dipropionate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 known ✓ P04150 7/20 0.88
▸ CYP3A4 P08684 9/20 0.88
▸ PGR P06401 6/20 0.88
▸ HIF1A Q16665 5/20 0.88
▸ USP2 O75604 4/20 0.88
▸ AR P10275 3/20 0.88
▸ ADORA3 P0DMS8 2/20 0.88
▸ CHRM1 P11229 1/20 0.88
▸ CNR1 P21554 1/20 0.88
▸ TBXA2R P21731 1/20 0.88
▸ MAPT P10636 3/20 0.75
▸ ABCB11 O95342 3/20 0.75
▸ LMNA P02545 3/20 0.75
▸ NFKB1 P19838 3/20 0.75
▸ SMN1; SMN2 Q16637 2/20 0.75
▸ BLM P54132 1/20 0.75
▸ GAA P10253 1/20 0.75
▸ NR1I2 O75469 2/20 0.71
▸ DRD2 P14416 1/20 0.71
▸ OPRD1 P41143 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Beclomethasone Dipropionate SCHEMBL28089907 0.95 CYP3A4 (0.80) CYP3A4NR3C1PGRHIF1AUSP2
Beclomethasone Dipropionate SCHEMBL3930412 0.94 CYP3A4 (0.97) CYP3A4NR3C1PGRHIF1AUSP2
Beclomethasone Dipropionate SCHEMBL2404673 0.94 CYP3A4 (1.00) CYP3A4NR3C1PGRHIF1AUSP2
Beclomethasone Dipropionate SCHEMBL13653326 0.94 CYP3A4 (1.00) CYP3A4NR3C1PGRHIF1AUSP2
Beclomethasone Dipropionate SCHEMBL19681908 0.94 CYP3A4 (1.00) CYP3A4NR3C1PGRHIF1AUSP2
Beclomethasone Dipropionate SCHEMBL6055713 0.94 CYP3A4 (1.00) CYP3A4NR3C1PGRHIF1AUSP2
Beclomethasone Dipropionate SCHEMBL6055708 0.94 CYP3A4 (1.00) CYP3A4NR3C1PGRHIF1AUSP2
Beclomethasone Dipropionate SCHEMBL5095 0.94 CYP3A4 (1.00) CYP3A4NR3C1PGRHIF1AUSP2
Beclomethasone Dipropionate SCHEMBL6941956 0.94 CYP3A4 (1.00) CYP3A4NR3C1PGRHIF1AUSP2
Beclomethasone Dipropionate SCHEMBL10493593 0.94 CYP3A4 (1.00) CYP3A4NR3C1PGRHIF1AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7704985-B2 Treatment of irritable bowel syndrome and related bowel diseases THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-04-27 — — US claimed
US-9044448-B2 X-ray contrast media compositions and methods of using the same 3E THERAPEUTICS CORPORATION (US) 2015-06-02 — — US disclosed
US-9044449-B2 X-ray contrast media compositions and methods of using the same to treat, reduce or delay the onset of CNS inflammation and inflammation associated conditions 3E THERAPEUTICS CORPORATION (US) 2015-06-02 — — US disclosed
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