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Beclomethasone Dipropionate

Beclomethasone Dipropionate

SCHEMBL28089907

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nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

NR3C1

The experimentally established mechanism targets of Beclomethasone Dipropionate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 known ✓ P04150 7/20 0.80
▸ CYP3A4 P08684 10/20 0.80
▸ PGR P06401 6/20 0.80
▸ USP2 O75604 5/20 0.80
▸ HIF1A Q16665 5/20 0.80
▸ MAPT P10636 3/20 0.80
▸ AR P10275 3/20 0.80
▸ ADORA3 P0DMS8 2/20 0.80
▸ NR1I2 O75469 2/20 0.80
▸ DRD2 P14416 1/20 0.80
▸ OPRD1 P41143 1/20 0.80
▸ CHRM1 P11229 1/20 0.80
▸ CNR1 P21554 1/20 0.80
▸ TBXA2R P21731 1/20 0.80
▸ LMNA P02545 3/20 0.70
▸ ABCB11 O95342 2/20 0.70
▸ SMN1; SMN2 Q16637 2/20 0.70
▸ NPSR1 Q6W5P4 2/20 0.70
▸ CYP2D6 P10635 2/20 0.70
▸ MLNR O43193 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Betamethasone Dipropionate SCHEMBL667603 0.95 NR3C1 (0.88) CYP3A4NR3C1PGRUSP2HIF1A
Beclomethasone Dipropionate SCHEMBL3425925 0.95 CYP3A4 (0.88) CYP3A4NR3C1PGRUSP2HIF1A
Beclomethasone Dipropionate SCHEMBL4461051 0.94 NR3C1 (0.90) CYP3A4NR3C1PGRUSP2HIF1A
Beclomethasone Dipropionate SCHEMBL3930412 0.89 CYP3A4 (0.97) CYP3A4NR3C1PGRUSP2HIF1A
Beclomethasone Dipropionate SCHEMBL10493593 0.89 CYP3A4 (1.00) CYP3A4NR3C1PGRUSP2HIF1A
Beclomethasone Dipropionate SCHEMBL6055708 0.89 CYP3A4 (1.00) CYP3A4NR3C1PGRUSP2HIF1A
Beclomethasone Dipropionate SCHEMBL13653326 0.89 CYP3A4 (1.00) CYP3A4NR3C1PGRUSP2HIF1A
Beclomethasone Dipropionate SCHEMBL6941956 0.89 CYP3A4 (1.00) CYP3A4NR3C1PGRUSP2HIF1A
Beclomethasone Dipropionate SCHEMBL9768491 0.89 CYP3A4 (1.00) CYP3A4NR3C1PGRUSP2HIF1A
Beclomethasone Dipropionate SCHEMBL10392062 0.89 CYP3A4 (1.00) CYP3A4NR3C1PGRUSP2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106278999-B S1P regulator 比奥根MA公司 2019-10-25 — — CN disclosed
CN-106278999-A S1p regulator 比奥根MA公司 2017-01-04 — — CN disclosed
CN-103533835-B S1P modulators 比奥根MA公司 2016-08-24 — — CN disclosed
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