Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4985483 | 0.85 | RAB9A (0.50) | NPC1RAB9ASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL5476348 | 0.84 | POLB (0.34) | NPC1RAB9ASMN1; SMN2KDM4EGLA | |
| SCHEMBL5481582 | 0.84 | POLB (0.34) | NPC1RAB9ASMN1; SMN2KDM4EGLA | |
| SCHEMBL3430680 | 0.83 | SMN1; SMN2 (0.39) | NPC1RAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL12468731 | 0.79 | SMN1; SMN2 (0.41) | NPC1RAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL1558873 | 0.78 | NAMPT (0.45) | NPC1RAB9APOLBLMNAKMT2A | |
| SCHEMBL1906809 | 0.76 | HSD17B10 (0.41) | NPC1RAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL3428561 | 0.76 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL11546313 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4EGLAPOLBCYP1A2 | |
| SCHEMBL1416126 | 0.74 | HPGD (0.49) | NPC1RAB9ASMN1; SMN2KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010146351-A1 | INDOLYLMETHYL-MORPHOLINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2010-12-23 | — | — | WO | disclosed |