Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 8/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 8/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 8/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 8/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.37 |
| ▸ | DDO | Q99489 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3424330 | 0.89 | ADRA2A (0.44) | DAOMETGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3359777 | 0.86 | MEN1 (0.43) | DAOMETGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3359580 | 0.86 | ADRA2A (0.49) | DAOMETGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3425826 | 0.84 | DAO (0.37) | DAOMETGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3360284 | 0.75 | GRIN2D (0.60) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3391960 | 0.69 | GRIN2D (0.38) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7027217 | 0.68 | HTT (0.42) | DAOHTTPTK2BADRA2ACLCN2 | |
| SCHEMBL3420842 | 0.68 | DAO (0.38) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3360150 | 0.68 | DAO (0.59) | DAOHTTGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3359927 | 0.68 | GRIN2D (0.45) | DAOGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |