Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 4/20 | 0.38 |
| ▸ | DDO | Q99489 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3425826 | 0.86 | DAO (0.37) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3422531 | 0.75 | DAO (0.51) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3424330 | 0.72 | ADRA2A (0.44) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3421760 | 0.72 | DAO (0.55) | DAODDO | |
| SCHEMBL3420696 | 0.72 | DAO (0.51) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3420415 | 0.69 | PGR (0.39) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3426119 | 0.68 | DAO (0.41) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3363824 | 0.68 | DAO (0.46) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3432547 | 0.68 | GRIN2D (0.41) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL13563277 | 0.68 | GABRA1 (0.50) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |