SCHEMBL3426366

SCHEMBL3426366

CCC(Cc1ccccc1)(C(=O)c1ccc(F)cc1)N(C)C

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 1/20 0.42
ACKR3 P25106 1/20 0.41
TMEM97 Q5BJF2 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
ALDH1A1 P00352 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
RIPK1 Q13546 2/20 0.40
LIMK2 P53671 1/20 0.39
TAS2R14 Q9NYV8 1/20 0.39
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Dichloroethane SCHEMBL28209044 0.95 MLYCD (0.39) MLYCDACKR3TMEM97SIGMAR1L3MBTL1
SCHEMBL28209045 0.94 NPC1 (0.39) MLYCDACKR3TMEM97SIGMAR1L3MBTL1
SCHEMBL2704437 0.93 RIPK1 (0.46) MLYCDALDH1A1RIPK1KDM4E
SCHEMBL8898870 0.93 MLYCD (0.45) MLYCDACKR3TMEM97SIGMAR1L3MBTL1
SCHEMBL17269409 0.90 NR4A2 (0.43) ALDH1A1RIPK1TAS2R14KDM4E
SCHEMBL4650526 0.90 RIPK1 (0.43) MLYCDNPC1RAB9ASMN1; SMN2RIPK1
Benzene SCHEMBL28672020 0.90 RIPK1 (0.43) MLYCDNPC1RAB9ASMN1; SMN2RIPK1
SCHEMBL19601191 0.88 SMN1; SMN2 (0.43) ALDH1A1SMN1; SMN2RIPK1TAS2R14KDM4E
SCHEMBL3428114 0.88 RIPK1 (0.42) NPC1RAB9AALDH1A1SMN1; SMN2RIPK1
SCHEMBL8899758 0.87 PPARG (0.48) MLYCDTMEM97SIGMAR1L3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105384707-B A kind of preparation method of α amino acetophenones light trigger 山东久日化学科技有限公司 2018-04-17 CN claimed
US-10961405-B2 Fluorine-containing acetophenone derivative, fluroine based additive, curable composition including same, and cured product thereof DIC CORPORATION (JP) 2021-03-30 US disclosed
WO-2019198489-A1 PHOTOSENSITIVE RESIN COMPOSITION, CURED PRODUCT, INSULATING MATERIAL, RESIN MATERIAL FOR SOLDER RESISTS AND RESIST MEMBER DIC株式会社 2019-10-17 WO disclosed
CN-105384707-B A kind of preparation method of α amino acetophenones light trigger 山东久日化学科技有限公司 2018-04-17 CN disclosed
CN-104974053-B Novel aminoketones photoinitiator and application in UV-LED photocuring system 天津久日新材料股份有限公司 2017-04-26 CN disclosed
EP-2379512-B1 TRI-FUNCTIONAL UV-ABSORBING COMPOUNDS AND USE THEREOF NOVARTIS AG (CH) 2017-03-29 EP disclosed
EP-2664629-B1 Functionalised photoinitiators BASF SE (DE) 2014-11-12 EP disclosed
EP-1711862-B1 FUNCTIONALIZED PHOTOINITIATORS BASF SE (DE) 2014-09-10 EP disclosed
EP-2664629-A1 Functionalised photoinitiators Ciba Holding Inc. (CH) 2013-11-20 EP disclosed
CN-103360272-A Quaternary ammonium salt preparation method and application thereof BEIJING INSIGHT HIGH TECHNOLOGY CO LTD 2013-10-23 CN disclosed
WO-2005076074-A2 FUNCTIONALIZED PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-08-18 WO disclosed
CN-1202098-C Novel morpholinone derivatives, process for producing the same and use thereof QITAI SCI TECH CO LTD (CN) 2005-05-18 CN disclosed
CN-1453272-A Novel morpholinone derivatives, process for producing the same and use thereof QITAI SCI TECH CO LTD (CN) 2003-11-05 CN disclosed
US-6022906-A α-aminoacetophenone photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-02-08 US disclosed
US-5629356-A PHOTOCURABLE COMPOSITION CONTAINING ETHYLENICALLY UNSATURATED PHOTOPOLYMERIZABLE COMPOUND AND THE AMINOACETOPHENONE CIBA GEIGY CORPORATION (US) 1997-05-13 US disclosed
US-5554663-A α-aminoacetophenones as photoinitiators CIBA-GEIGY CORPORATION (US) 1996-09-10 US disclosed
US-5534629-A PHOTOPOLYMERIZATION OF PIGMENTED SYSTEMS, INKS CIBA-GEIGY CORPORATION (US) 1996-07-09 US disclosed
EP-0284561-B1 ALPHA-AMINOACETOPHENONES AS PHOTO INITIATORS CIBA-GEIGY AG (CH) 1993-05-12 EP disclosed
US-5077402-A For photocuring pigmented systems; printing inks, lacquers CIBA-GEIGY CORPORATION (US) 1991-12-31 US disclosed
EP-0284561-A2 Alpha-aminoacetophenones as photo initiators CIBA-GEIGY AG (CH) 1988-09-28 EP disclosed