SCHEMBL8899758

SCHEMBL8899758

CCC(Cc1ccccc1)(C(=O)c1ccc(Cl)cc1)N(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.48
PPARA Q07869 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.46
MAPT P10636 1/20 0.46
TMEM97 Q5BJF2 4/20 0.44
SIGMAR1 Q99720 4/20 0.44
GABRB1 P18505 1/20 0.42
GABRB2 P47870 1/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
MLYCD O95822 1/20 0.40
GRIN2B Q13224 1/20 0.40
TP53 P04637 1/20 0.39
TAS2R14 Q9NYV8 2/20 0.39
MEN1 O00255 1/20 0.39
CXCR3 P49682 1/20 0.39
KMT2A Q03164 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28672020 0.91 RIPK1 (0.43) CES2CES1NPC1RAB9AMLYCD
SCHEMBL4650526 0.91 RIPK1 (0.43) CES2CES1NPC1RAB9AMLYCD
SCHEMBL8898989 0.89 TMEM97 (0.43) PPARGPPARAL3MBTL1MAPTTMEM97
SCHEMBL4651747 0.89 NPC1 (0.41) L3MBTL1MAPTCES2CES1NPC1
SCHEMBL8898890 0.89 LMNA (0.42) MAPTCES2MLYCDTAS2R14RIPK1
SCHEMBL8896958 0.87 TMEM97 (0.41) L3MBTL1MAPTTMEM97SIGMAR1RAB9A
SCHEMBL3426366 0.87 MLYCD (0.42) L3MBTL1TMEM97SIGMAR1NPC1RAB9A
SCHEMBL58499 0.87 KMT2A (0.51) MAPTNPC1RAB9AMLYCDMEN1
SCHEMBL8899987 0.87 MLYCD (0.39) PPARGPPARAMAPTNPC1RAB9A
SCHEMBL8897856 0.87 TMEM97 (0.45) PPARGPPARATMEM97SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5629356-A PHOTOCURABLE COMPOSITION CONTAINING ETHYLENICALLY UNSATURATED PHOTOPOLYMERIZABLE COMPOUND AND THE AMINOACETOPHENONE CIBA GEIGY CORPORATION (US) 1997-05-13 US disclosed
US-5554663-A α-aminoacetophenones as photoinitiators CIBA-GEIGY CORPORATION (US) 1996-09-10 US disclosed
US-5534629-A PHOTOPOLYMERIZATION OF PIGMENTED SYSTEMS, INKS CIBA-GEIGY CORPORATION (US) 1996-07-09 US disclosed
US-5306600-A Oxygen-containing titanocenes, and the use thereof CIBA-GEIGY CORPORATION (US) 1994-04-26 US disclosed
EP-0284561-B1 ALPHA-AMINOACETOPHENONES AS PHOTO INITIATORS CIBA-GEIGY AG (CH) 1993-05-12 EP disclosed
US-5192642-A Photoinitiators for addition photopolymerization, coatings CIBA-GEIGY CORPORATION (US) 1993-03-09 US disclosed
US-5077402-A For photocuring pigmented systems; printing inks, lacquers CIBA-GEIGY CORPORATION (US) 1991-12-31 US disclosed
US-5068371-A Photoinitiators for polymerization CIBA-GEIGY CORPORATION (US) 1991-11-26 US disclosed
EP-0284561-A2 Alpha-aminoacetophenones as photo initiators CIBA-GEIGY AG (CH) 1988-09-28 EP disclosed