Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675320 | 0.87 | METAP2 (0.39) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL5072700 | 0.81 | METAP2 (0.44) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL5828208 | 0.77 | METAP2 (0.44) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL9356684 | 0.77 | METAP2 (0.44) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL3421963 | 0.77 | METAP2 (0.44) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL5934354 | 0.74 | RIPK1 (0.40) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL1398868 | 0.74 | METAP2 (0.44) | METAP2METAP1ENPP1NPY5RGRIN2B | |
| SCHEMBL5436671 | 0.73 | METAP2 (0.41) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL28139921 | 0.73 | METAP2 (0.41) | METAP2METAP1ENPP1NPY5RGRIN2B | |
| SCHEMBL1551871 | 0.73 | RIPK1 (0.42) | METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790374-B2 | Process for sequence saturation mutagenesis (SeSaM) | BASF AKTIENGESELLSCHAFT (DE) | 2010-09-07 | — | — | US | claimed |
| EP-1670914-B1 | A PROCESS FOR SEQUENCE SATURATION MUTAGENESIS (SESAM) | BASF AG (DE) | 2008-01-23 | — | — | EP | claimed |
| EP-1670914-A1 | A PROCESS FOR SEQUENCE SATURATION MUTAGENESIS (SESAM) | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-21 | — | — | EP | claimed |
| WO-2005035757-A1 | A PROCESS FOR SEQUENCE SATURATION MUTAGENESIS (SESAM) | BASF AKTIENGESELLSCHAFT (DE) | 2005-04-21 | — | — | WO | claimed |
| US-7790374-B2 | Process for sequence saturation mutagenesis (SeSaM) | BASF AKTIENGESELLSCHAFT (DE) | 2010-09-07 | — | — | US | disclosed |
| EP-1670914-B1 | A PROCESS FOR SEQUENCE SATURATION MUTAGENESIS (SESAM) | BASF AG (DE) | 2008-01-23 | — | — | EP | disclosed |
| US-20060223148-A1 | Process for sequence saturation mutagenesis (sesam) | BASF AKTIENGESCHAFT (DE) | 2006-10-05 | — | — | US | disclosed |
| EP-1670914-A1 | A PROCESS FOR SEQUENCE SATURATION MUTAGENESIS (SESAM) | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005035757-A1 | A PROCESS FOR SEQUENCE SATURATION MUTAGENESIS (SESAM) | BASF AKTIENGESELLSCHAFT (DE) | 2005-04-21 | — | — | WO | disclosed |