Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3426596 | 0.87 | METAP2 (0.41) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL5072700 | 0.78 | METAP2 (0.44) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL3421963 | 0.75 | METAP2 (0.44) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL5828208 | 0.75 | METAP2 (0.44) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL9356684 | 0.75 | METAP2 (0.44) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL5934354 | 0.72 | RIPK1 (0.40) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL1398868 | 0.71 | METAP2 (0.44) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL5436671 | 0.71 | METAP2 (0.41) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL28139921 | 0.71 | METAP2 (0.41) | METAP2METAP1ENPP1NPY5R | |
| SCHEMBL10550428 | 0.71 | METAP2 (0.38) | METAP2METAP1ENPP1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004042078-A1 | NUCLEOTIDE SEQUENCE ANALYSIS BY QUANTIFICATION OF MUTAGENESIS | THE UNIVERSITY OF QUEENSLAND (AU) | 2004-05-21 | — | — | WO | disclosed |