Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 14/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10944570 | 0.82 | MAPK1 (0.35) | — | |
| SCHEMBL11053945 | 0.78 | TSHR (0.40) | — | |
| SCHEMBL11636230 | 0.77 | CYP1A2 (0.33) | — | |
| SCHEMBL8515614 | 0.75 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL260743 | 0.75 | NLRP3 (0.36) | — | |
| SCHEMBL259449 | 0.75 | NLRP3 (0.36) | — | |
| SCHEMBL8428847 | 0.75 | ALDH1A1 (0.44) | — | |
| SCHEMBL4304520 | 0.72 | TP53 (0.37) | — | |
| SCHEMBL10335808 | 0.72 | NPSR1 (0.33) | — | |
| SCHEMBL1686047 | 0.71 | SMN1; SMN2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3215513-B1 | FUNCTIONALIZED MORPHOLINYL ANTHRACYCLINE DERIVATIVES | NERVIANO MEDICAL SCIENCES SRL (IT) | 2019-05-08 | — | — | EP | disclosed |
| US-9826129-B2 | Near-infrared-ray-absorbing composition, near-infrared-ray cut filter using same, manufacturing method therefor, camera module, and manufacturing method therefor | FUJIFILM CORPORATION (JP) | 2017-11-21 | — | — | US | disclosed |
| US-9826129-B2 | Near-infrared-ray-absorbing composition, near-infrared-ray cut filter using same, manufacturing method therefor, camera module, and manufacturing method therefor | FUJIFILM CORPORATION (JP) | 2017-11-21 | — | — | US | disclosed |
| US-20170312290-A1 | FUNCTIONALIZED MORPHOLINYL ANTHRACYCLINE DERIVATIVES | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2017-11-02 | — | — | US | disclosed |
| EP-3215513-A1 | FUNCTIONALIZED MORPHOLINYL ANTHRACYCLINE DERIVATIVES | Nerviano Medical Sciences S.r.l. (IT) | 2017-09-13 | — | — | EP | disclosed |
| US-9695240-B2 | Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds | GENENTECH, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| WO-2016071418-A1 | FUNCTIONALIZED MORPHOLINYL ANTHRACYCLINE DERIVATIVES | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2016-05-12 | — | — | WO | disclosed |
| US-20160037034-A1 | NEAR-INFRARED-RAY-ABSORBING COMPOSITION, NEAR-INFRARED-RAY CUT FILTER USING SAME, MANUFACTURING METHOD THEREFOR, CAMERA MODULE, AND MANUFACTURING METHOD THEREFOR | FUJIFILM CORPORATION (JP) | 2016-02-04 | — | — | US | disclosed |
| US-20160037034-A1 | NEAR-INFRARED-RAY-ABSORBING COMPOSITION, NEAR-INFRARED-RAY CUT FILTER USING SAME, MANUFACTURING METHOD THEREFOR, CAMERA MODULE, AND MANUFACTURING METHOD THEREFOR | FUJIFILM CORPORATION (JP) | 2016-02-04 | — | — | US | disclosed |
| US-20150051380-A1 | ANTHRACYCLINE DERIVATIVE CONJUGATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR COMPOUNDS | GENENTECH, INC. (US) | 2015-02-19 | — | — | US | disclosed |
| EP-2303332-B1 | ANTHRACYCLINE CONJUGATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR COMPOUNDS | GENENTECH INC (US) | 2014-12-31 | — | — | EP | disclosed |
| US-8900589-B2 | Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds | GENETECH, INC. (US) | 2014-12-02 | — | — | US | disclosed |
| US-8389697-B2 | Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds | GENENTECH, INC. (US) | 2013-03-05 | — | — | US | disclosed |
| US-20120130059-A1 | ANTHRACYCLINE DERIVATIVE CONJUGATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR COMPOUNDS | BERIA ITALO (IT) | 2012-05-24 | — | — | US | disclosed |
| US-20100034837-A1 | ANTHRACYCLINE DERIVATIVE CONJUGATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR COMPOUNDS | GENENTECH, INC. | 2010-02-11 | — | — | US | disclosed |
| WO-2010009124-A2 | ANTHRACYCLINE DERIVATIVE CONJUGATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR COMPOUNDS | GENENTECH, INC. (US) | 2010-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160037034-A1 | NEAR-INFRARED-RAY-ABSORBING COMPOSITION, NEAR-INFRARED-RAY CUT FILTER USING SAME, MANUFACTURING METHOD THEREFOR, CAMERA MODULE, AND MANUFACTURING METHOD THEREFOR | FAR1, SLC39A11, NOTUM | PTGIR 2696/4885PTGDR 4655/4885PTGER1 2878/4885 |
| US-20170312290-A1 | FUNCTIONALIZED MORPHOLINYL ANTHRACYCLINE DERIVATIVES | CCNY, BCR, CCNB3 | PTGIR 4703/4885PTGDR 2278/4885PTGER1 4688/4885 |
| US-20150051380-A1 | ANTHRACYCLINE DERIVATIVE CONJUGATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR COMPOUNDS | MRPL21, BCR, MYD88 | PTGIR 4774/4885PTGDR 4104/4885PTGER1 4609/4885 |
| US-20100034837-A1 | ANTHRACYCLINE DERIVATIVE CONJUGATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR COMPOUNDS | MRPL21, BCR, MYD88 | PTGIR 4774/4885PTGDR 4104/4885PTGER1 4609/4885 |
| US-20120130059-A1 | ANTHRACYCLINE DERIVATIVE CONJUGATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR COMPOUNDS | MRPL21, BCR, MYD88 | PTGIR 4774/4885PTGDR 4104/4885PTGER1 4609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.