SCHEMBL8428847

SCHEMBL8428847

O=C(CCC(=O)OCC1CCC=CO1)OCC1CCC=CO1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
LMNA P02545 2/20 0.42
POLB P06746 1/20 0.42
MGLL Q99685 3/20 0.34
LPAR1 Q92633 2/20 0.34
LPAR3 Q9UBY5 2/20 0.34
USP2 O75604 1/20 0.34
ALOX15 P16050 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8429838 0.93 LMNA (0.47) ALDH1A1LMNAPOLBMGLLLPAR1
SCHEMBL18570723 0.93 LMNA (0.51) ALDH1A1LMNAPOLBMGLLLPAR1
SCHEMBL11640528 0.87 LMNA (0.34) ALDH1A1LMNAPOLBLPAR1LPAR3
SCHEMBL18025584 0.87 LMNA (0.36) ALDH1A1LMNAPOLBLPAR1LPAR3
SCHEMBL19941729 0.87 ADRA2A (0.41) ALDH1A1LMNAPOLBLPAR1LPAR3
SCHEMBL260743 0.83 NLRP3 (0.36) ALDH1A1LMNA
SCHEMBL259449 0.83 NLRP3 (0.36) ALDH1A1LMNA
SCHEMBL28462428 0.83 TP53 (0.32)
SCHEMBL4304520 0.80 TP53 (0.37) LMNA
SCHEMBL25299768 0.78 MGLL (0.43) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5863996-A ADDITION POLYMERIZATION AND CROSSLINKING THEN GELATION TO FORM PARTICLES NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1999-01-26 US disclosed
EP-0155704-B1 BLENDS OF CYCLIC VINYL ETHER CONTAINING COMPOUNDS AND URETHANE ACRYLATES UNION CARBIDE CORPORATION (US) 1990-06-06 EP disclosed
US-4920156-A Photocurable coatings; flexibility, impact strength UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) 1990-04-24 US disclosed
US-4840978-A FLEXIBILITY, IMPACT RESISTANT COATINGS UNION CARBIDE CORPORATION (US) 1989-06-20 US disclosed
EP-0123912-B1 BLENDS OF CYCLIC VINYL ETHER CONTAINING COMPOUNDS AND EPOXIDES UNION CARBIDE CORPORATION (US) 1987-09-09 EP disclosed
US-4645781-A PHOTOCOPOLYMERIZABLE UNION CARBIDE CORPORATION (US) 1987-02-24 US disclosed
EP-0155704-A2 Blends of cyclic vinyl ether containing compounds and urethane acrylates UNION CARBIDE CORPORATION (US) 1985-09-25 EP disclosed
EP-0123912-A1 Blends of cyclic vinyl ether containing compounds and epoxides UNION CARBIDE CORPORATION (US) 1984-11-07 EP disclosed
US-4009129-A FOAMING, CATIONIC CATALYSTS UNION CARBIDE CORPORATION (US) 1977-02-22 US disclosed