Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 9/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1110619 | 0.90 | SLC5A1 (0.52) | SLC5A1MEN1KMT2APTGS2EPHX2 | |
| SCHEMBL29074651 | 0.90 | SLC5A1 (0.51) | SLC5A1MEN1KMT2ANR3C1PGR | |
| SCHEMBL3428197 | 0.90 | RXRA (0.52) | SLC5A1MEN1KMT2APTGS2EPHX2 | |
| SCHEMBL3430105 | 0.87 | KMT2A (0.54) | SLC5A1MEN1KMT2APTGS2LMNA | |
| SCHEMBL25396677 | 0.87 | SLC5A1 (0.50) | SLC5A1MEN1KMT2ANR3C1PGR | |
| SCHEMBL3430065 | 0.86 | RPA1 (0.44) | SLC5A1KMT2APTGS2EPHX2 | |
| SCHEMBL1110794 | 0.86 | PPP1CA (0.46) | SLC5A1MEN1KMT2APTGS2PPP1CA | |
| SCHEMBL3431585 | 0.86 | SLC5A1 (0.48) | SLC5A1MEN1KMT2ANR3C1PGR | |
| SCHEMBL3431908 | 0.84 | KMT2A (0.51) | SLC5A1MEN1KMT2APTGS2ALDH1A1 | |
| SCHEMBL1110894 | 0.84 | SLC16A3 (0.48) | SLC5A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254885-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AiCuris GmbH & Co. KG (DE) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009115213-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AICURIS GMBH & CO. KG (DE) | 2009-09-24 | — | — | WO | disclosed |