Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.52 |
| ▸ | RXRB | P28702 | 1/20 | 0.52 |
| ▸ | RXRG | P48443 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC5A1 | P13866 | 7/20 | 0.45 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.44 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.44 |
| ▸ | RPA1 | P27694 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1110794 | 0.91 | PPP1CA (0.46) | RXRARXRBRXRGPTGS2SLC5A1 | |
| SCHEMBL3426741 | 0.90 | SLC5A1 (0.52) | PTGS2SLC5A1MEN1KMT2AEPHX2 | |
| SCHEMBL3430065 | 0.90 | RPA1 (0.44) | RXRARXRBRXRGPTGS2SLC5A1 | |
| SCHEMBL1110619 | 0.89 | SLC5A1 (0.52) | PTGS2PTGS1SLC5A1RPA1MEN1 | |
| SCHEMBL3427747 | 0.88 | KMT2A (0.49) | RXRARXRBRXRGPTGS2SLC5A1 | |
| SCHEMBL3430698 | 0.86 | PPP1CA (0.52) | RXRARXRBRXRGSLC16A3SLC16A1 | |
| SCHEMBL3431433 | 0.86 | RXRA (0.47) | RXRARXRBRXRGPTGS2PTGS1 | |
| SCHEMBL3428213 | 0.85 | MEN1 (0.51) | RXRARXRBRXRGPTGS2SLC16A3 | |
| SCHEMBL7156590 | 0.85 | MALT1 (0.58) | SLC16A3SLC16A1RPA1SMN1; SMN2MALT1 | |
| SCHEMBL3429834 | 0.83 | RXRA (0.50) | RXRARXRBRXRGPTGS2SLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254885-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AiCuris GmbH & Co. KG (DE) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009115213-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AICURIS GMBH & CO. KG (DE) | 2009-09-24 | — | — | WO | disclosed |