SCHEMBL3426787

SCHEMBL3426787

O=C(N[Hf])c1ccccn1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HDAC6 Q9UBN7 2/20 0.61
▸ HDAC3 O15379 1/20 0.61
▸ HDAC4 P56524 1/20 0.61
▸ HDAC1 Q13547 1/20 0.61
▸ HDAC7 Q8WUI4 1/20 0.61
▸ HDAC2 Q92769 1/20 0.61
▸ HDAC10 Q969S8 1/20 0.61
▸ HDAC11 Q96DB2 1/20 0.61
▸ HDAC8 Q9BY41 1/20 0.61
▸ HDAC9 Q9UKV0 1/20 0.61
▸ HDAC5 Q9UQL6 1/20 0.61
▸ CES2 O00748 1/20 0.59
▸ CES1 P23141 1/20 0.59
▸ LMNA P02545 3/20 0.57
▸ L3MBTL1 Q9Y468 2/20 0.57
▸ NAPRT Q6XQN6 1/20 0.57
▸ P4HTM Q9NXG6 1/20 0.57
▸ ALDH1A1 P00352 3/20 0.55
▸ KMT2A Q03164 4/20 0.54
▸ SMN1; SMN2 Q16637 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4508472 0.83 CES2 (0.64) HDAC6HDAC3HDAC4HDAC1HDAC7
SCHEMBL1147702 0.83 KDM4E (0.73) CES2CES1LMNAL3MBTL1NAPRT
SCHEMBL1422257 0.81 CES2 (0.61) HDAC6HDAC3HDAC4HDAC1HDAC7
SCHEMBL1412816 0.81 CES2 (0.61) HDAC6HDAC3HDAC4HDAC1HDAC7
SCHEMBL11223392 0.81 CES2 (0.61) HDAC6HDAC3HDAC4HDAC1HDAC7
SCHEMBL28727383 0.81 CES2 (0.61) HDAC6HDAC3HDAC4HDAC1HDAC7
SCHEMBL23723198 0.79 CES2 (0.59) HDAC6HDAC3HDAC4HDAC1HDAC7
SCHEMBL162189 0.79 ALDH1A1 (0.61) HDAC6HDAC3HDAC4HDAC1HDAC7
SCHEMBL4754862 0.79 CES2 (0.59) HDAC6HDAC3HDAC4HDAC1HDAC7
SCHEMBL7989152 0.79 HDAC1 (0.77) HDAC6HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220389209-A1 POLYETHYLENE AND POLYPROPYLENE BLOCK COPOLYMERS CORNELL UNIVERSITY (US) 2022-12-08 — — US claimed
EP-4028432-A1 GRAFT COPOLYMERS FOR COMPATIBILIZATION OF POLYETHYLENE AND POLYPROPYLENE Cornell University (US) 2022-07-20 — — EP claimed
US-11279780-B2 Polyethylene and polypropylene block copolymers CORNELL UNIVERSITY (US) 2022-03-22 — — US claimed
WO-2021051103-A1 GRAFT COPOLYMERS FOR COMPATIBILIZATION OF POLYETHYLENE AND POLYPROPYLENE CORNELL UNIVERSITY (US) 2021-03-18 — — WO claimed
US-20190300631-A1 POLYETHYLENE AND POLYPROPYLENE BLOCK COPOLYMERS CORNELL UNIVERSITY (US) 2019-10-03 — — US claimed
WO-2017205774-A1 POLYETHYLENE AND POLYPROPYLENE BLOCK COPOLYMERS CORNELL UNIVERSITY (US) 2017-11-30 — — WO claimed
US-11987653-B1 Olefin polymerizations and printing methods thereof UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2024-05-21 — — US disclosed
US-20230279173-A1 Compositions Based on Multi-Block Polyolefin Copolymers Kraton Corporation (US) 2023-09-07 — — US disclosed
EP-4239024-A2 COMPOSITIONS BASED ON MULTI-BLOCK POLYOLEFIN COPOLYMERS Kraton Polymers Nederland B.V. (NL) 2023-09-06 — — EP disclosed
CN-115947882-A Preparation method of pyridine amido hafnium catalyst 江苏欣诺科催化剂股份有限公司 2023-04-11 — — CN disclosed
CN-115947882-A Preparation method of pyridine amido hafnium catalyst 江苏欣诺科催化剂股份有限公司 2023-04-11 — — CN disclosed
CN-115947882-A Preparation method of pyridine amido hafnium catalyst 江苏欣诺科催化剂股份有限公司 2023-04-11 — — CN disclosed
US-20230002535-A1 Anionic Polymerization Initiator, Anionic Polymerization Initiator Composition, and Production Method Therefor LG CHEM, LTD. (KR) 2023-01-05 — — US disclosed
WO-2021051103-A1 GRAFT COPOLYMERS FOR COMPATIBILIZATION OF POLYETHYLENE AND POLYPROPYLENE CORNELL UNIVERSITY (US) 2021-03-18 — — WO disclosed
US-20190300631-A1 POLYETHYLENE AND POLYPROPYLENE BLOCK COPOLYMERS CORNELL UNIVERSITY (US) 2019-10-03 — — US disclosed
WO-2017205774-A1 POLYETHYLENE AND POLYPROPYLENE BLOCK COPOLYMERS CORNELL UNIVERSITY (US) 2017-11-30 — — WO disclosed
WO-2010148381-A2 GROUP IV OLEFIN POLYMERIZATION CATALYSTS AND POLYMERIZATION METHODS CORNELL UNIVERSITY (US) 2010-12-23 — — WO disclosed
WO-2008112133-A3 PYRIDLYAMIDOHAFNIUM CATALYST PRECURSORS, ACTIVE SPECIES FROM THIS AND USES THEREOF TO POLYMERIZE ALKENES UNIV CORNELL (US) 2008-11-06 — — WO disclosed
WO-2008112133-A2 PYRIDLYAMIDOHAFNIUM CATALYST PRECURSORS, ACTIVE SPECIES FROM THIS AND USES THEREOF TO POLYMERIZE ALKENES CORNELL UNIVERSITY (US) 2008-09-18 — — WO disclosed
WO-2008112133-A2 PYRIDLYAMIDOHAFNIUM CATALYST PRECURSORS, ACTIVE SPECIES FROM THIS AND USES THEREOF TO POLYMERIZE ALKENES CORNELL UNIVERSITY (US) 2008-09-18 — — WO disclosed
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