Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.49 |
| ▸ | FASN | P49327 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318335 | 0.82 | MAOA (0.66) | MAOAFASNMMP1PTPN1ACE | |
| SCHEMBL22031603 | 0.76 | ALDH1A1 (0.74) | MAOAKDRMCL1KDM4EALDH1A1 | |
| SCHEMBL6358791 | 0.75 | MCL1 (0.61) | MAOAFASNMMP1PTPN1ACE | |
| SCHEMBL26766939 | 0.74 | NPSR1 (0.67) | ACHEFTOMCL1KDM4EALDH1A1 | |
| SCHEMBL26767094 | 0.72 | PDE2A (0.68) | MAOAKDM4EALDH1A1THRBHPGD | |
| SCHEMBL14925261 | 0.72 | ALDH1A1 (0.55) | MCL1KDM4EALDH1A1CYP3A4THRB | |
| SCHEMBL23117750 | 0.72 | ALDH1A1 (0.55) | MCL1KDM4EALDH1A1CYP3A4THRB | |
| SCHEMBL20178964 | 0.72 | MAOA (0.50) | MAOAFASNMMP1PTPN1ACE | |
| SCHEMBL12433440 | 0.71 | MCL1 (0.54) | MCL1KDM4EALDH1A1CYP3A4THRB | |
| SCHEMBL31512480 | 0.71 | MAOA (0.69) | MAOAACEMCL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759459-B2 | Fluorescent assays for protein kinases | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2010-07-20 | — | — | US | disclosed |
| US-7759459-B2 | Fluorescent assays for protein kinases | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2010-07-20 | — | — | US | disclosed |
| US-7759459-B2 | Fluorescent assays for protein kinases | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2010-07-20 | — | — | US | disclosed |
| US-20050233467-A1 | Visible wavelength fluorescent calcium indicators that are (i) leakage resistant and (ii) operate near membranes | INVITROGEN CORP. | 2005-10-20 | — | — | US | disclosed |
| US-20050054024-A1 | Fluorescent assays for protein kinases | NATIONAL INSTITUTES OF HEALTH | 2005-03-10 | — | — | US | disclosed |
| WO-2004062475-A2 | FLUORESCENT ASSAYS FOR PROTEIN KINASES | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2004-07-29 | — | — | WO | disclosed |