SCHEMBL2318335

SCHEMBL2318335

O=c1c2cc(O)c(O)cc2oc2cc(O)c(O)cc12

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.66
MMP1 P03956 1/20 0.66
PTPN1 P18031 1/20 0.66
FASN P49327 1/20 0.66
ACE P12821 1/20 0.63
KDR P35968 2/20 0.57
MCL1 Q07820 6/20 0.55
AKR1B1 P15121 3/20 0.55
KDM4E B2RXH2 2/20 0.55
HPGD P15428 2/20 0.55
HSD17B10 Q99714 2/20 0.55
ALDH1A1 P00352 1/20 0.55
CYP3A4 P08684 1/20 0.55
THRB P10828 1/20 0.55
ALOX15 P16050 3/20 0.50
ALOX12 P18054 2/20 0.47
TP53 P04637 1/20 0.47
MAPT P10636 1/20 0.47
CYP19A1 P11511 1/20 0.47
CASP1 P29466 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1954261 0.86 MAOA (0.69) MAOAACEMCL1KDM4EHPGD
SCHEMBL31512480 0.86 MAOA (0.69) MAOAACEMCL1KDM4EHPGD
SCHEMBL3887841 0.84 KDR (0.54) MAOAMMP1PTPN1FASNACE
SCHEMBL20178964 0.83 MAOA (0.50) MAOAMMP1PTPN1FASNACE
SCHEMBL3426822 0.82 MAOA (0.49) MAOAMMP1PTPN1FASNACE
SCHEMBL6358791 0.82 MCL1 (0.61) MAOAMMP1PTPN1FASNACE
SCHEMBL31573813 0.80 MAOA (0.69) MAOAMMP1PTPN1FASNACE
SCHEMBL2418732 0.80 MAOA (1.00) MAOAMMP1PTPN1FASNACE
SCHEMBL29678199 0.80 MAOA (1.00) MAOAMMP1PTPN1FASNACE
SCHEMBL29908959 0.80 MAOA (1.00) MAOAMMP1PTPN1FASNACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9062022-B2 Polymer composition and dialysis membrane formed from the polymer composition THE UNIVERSITY OF AKRON (US) 2015-06-23 US claimed
EP-2373638-A1 POLYMER COMPOSITION AND DIALYSIS MEMBRANE FORMED FROM THE POLYMER COMPOSITION The University of Akron (US) 2011-10-12 EP claimed
US-20110233138-A1 POLYMER COMPOSITION AND DIALYSIS MEMBRANE FORMED FROM THE POLYMER COMPOSITION THE UNIVERSITY OF AKRON 2011-09-29 US claimed
WO-2010065484-A1 POLYMER COMPOSITION AND DIALYSIS MEMBRANE FORMED FROM THE POLYMER COMPOSITION THE UNIVERSITY OF AKRON (US) 2010-06-10 WO claimed
US-9062022-B2 Polymer composition and dialysis membrane formed from the polymer composition THE UNIVERSITY OF AKRON (US) 2015-06-23 US disclosed
US-9062022-B2 Polymer composition and dialysis membrane formed from the polymer composition THE UNIVERSITY OF AKRON (US) 2015-06-23 US disclosed
US-9062022-B2 Polymer composition and dialysis membrane formed from the polymer composition THE UNIVERSITY OF AKRON (US) 2015-06-23 US disclosed
US-8883010-B2 Polymer composition with phytochemical and dialysis membrane formed from the polymer composition THE UNIVERSITY OF AKRON (US) 2014-11-11 US disclosed
EP-2558088-A1 POLYMER COMPOSITION WITH PHYTOCHEMICAL AND DIALYSIS MEMBRANE FORMED FROM THE POLYMER COMPOSITION The University of Akron (US) 2013-02-20 EP disclosed
WO-2011130206-A1 POLYMER COMPOSITION WITH PHYTOCHEMICAL AND DIALYSIS MEMBRANE FORMED FROM THE POLYMER COMPOSITION THE UNIVERSITY OF AKRON (US) 2011-10-20 WO disclosed
EP-2373638-A1 POLYMER COMPOSITION AND DIALYSIS MEMBRANE FORMED FROM THE POLYMER COMPOSITION The University of Akron (US) 2011-10-12 EP disclosed
US-20110233138-A1 POLYMER COMPOSITION AND DIALYSIS MEMBRANE FORMED FROM THE POLYMER COMPOSITION THE UNIVERSITY OF AKRON 2011-09-29 US disclosed
US-20110233138-A1 POLYMER COMPOSITION AND DIALYSIS MEMBRANE FORMED FROM THE POLYMER COMPOSITION THE UNIVERSITY OF AKRON 2011-09-29 US disclosed
US-20110233138-A1 POLYMER COMPOSITION AND DIALYSIS MEMBRANE FORMED FROM THE POLYMER COMPOSITION THE UNIVERSITY OF AKRON 2011-09-29 US disclosed
US-20110186518-A1 POLYMER COMPOSITION WITH PHYTOCHEMICAL AND DIALYSIS MEMBRANE FORMED FROM THE POLYMER COMPOSITION THE UNIVERSITY OF AKRON (US) 2011-08-04 US disclosed
WO-2010065484-A1 POLYMER COMPOSITION AND DIALYSIS MEMBRANE FORMED FROM THE POLYMER COMPOSITION THE UNIVERSITY OF AKRON (US) 2010-06-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110186518-A1 POLYMER COMPOSITION WITH PHYTOCHEMICAL AND DIALYSIS MEMBRANE FORMED FROM THE POLYMER COMPOSITION MATR3, ATP6V1B1, CD68 MAOA 2005/4885MMP1 21/4885PTPN1 4054/4885
US-20110233138-A1 POLYMER COMPOSITION AND DIALYSIS MEMBRANE FORMED FROM THE POLYMER COMPOSITION PROC, LNPK, F10 MAOA 2542/4885MMP1 467/4885PTPN1 3907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.