Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1895297 | 0.92 | HTT (0.58) | SMN1; SMN2LMNAL3MBTL1MAPTHTT | |
| SCHEMBL5724218 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAL3MBTL1MAPTHTT | |
| SCHEMBL19438891 | 0.82 | CHRNB2 (0.57) | SMN1; SMN2L3MBTL1HTTKMT2A | |
| SCHEMBL30938203 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAHTT | |
| SCHEMBL31480636 | 0.82 | LTA4H (0.46) | SMN1; SMN2LMNAL3MBTL1MAPTCA1 | |
| SCHEMBL26129282 | 0.81 | NPC1 (0.47) | — | |
| SCHEMBL16757577 | 0.81 | LTA4H (0.44) | SMN1; SMN2LMNAL3MBTL1MAPTHTT | |
| SCHEMBL6240402 | 0.81 | HTT (0.56) | SMN1; SMN2LMNAL3MBTL1MAPTHTT | |
| SCHEMBL28948064 | 0.80 | LMNA (0.44) | SMN1; SMN2LMNAL3MBTL1MAPTHTT | |
| SCHEMBL28948076 | 0.80 | LMNA (0.44) | SMN1; SMN2LMNAL3MBTL1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025061148-A1 | HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2025-03-27 | — | — | WO | disclosed |
| WO-2015197872-A1 | DERIVATIVES OF OSW-1 AND USE THEREOF FOR THE TREATMENT OF CANCER | PIERRE FABRE MEDICAMENT (FR) | 2015-12-30 | — | — | WO | disclosed |
| US-8481502-B2 | Antibacterial aminoglycoside analogs | ACHAOGEN, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| WO-2010027280-A1 | NITROBENZINDOLES AND THEIR USE IN CANCER THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 2010-03-11 | — | — | WO | disclosed |