Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.59 |
| ▸ | ATIC | P31939 | 1/20 | 0.58 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | PHLPP2 | Q6ZVD8 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17951495 | 0.88 | POLB (0.68) | POLBCYP2D6RPS6KA3ATICGLO1 | |
| SCHEMBL5408798 | 0.83 | ATIC (0.59) | POLBCYP2D6RPS6KA3ATICGLO1 | |
| SCHEMBL18624977 | 0.80 | POLB (0.83) | POLBCYP2D6RPS6KA3ATICGLO1 | |
| SCHEMBL28560987 | 0.80 | POLB (0.83) | POLBCYP2D6RPS6KA3ATICGLO1 | |
| SCHEMBL5364165 | 0.79 | RPS6KA3 (0.62) | POLBCYP2D6RPS6KA3ATICGLO1 | |
| SCHEMBL24187557 | 0.79 | ATIC (0.81) | POLBCYP2D6RPS6KA3ATICGLO1 | |
| SCHEMBL131176 | 0.78 | MEN1 (0.56) | POLBCYP2D6GLO1CA2HSD17B10 | |
| SCHEMBL6125745 | 0.77 | POLB (0.66) | POLBCYP2D6RPS6KA3ATICGLO1 | |
| SCHEMBL8947084 | 0.77 | POLB (0.66) | POLBCYP2D6RPS6KA3ATICGLO1 | |
| SCHEMBL3917038 | 0.76 | ATIC (0.58) | POLBCYP2D6RPS6KA3ATICGLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150148317-A1 | SPINAL CORD INJURY, INFLAMMATION, AND IMMUNE-DISEASE: LOCAL CONTROLLED RELEASE OF THERAPEUTIC AGENTS | INVIVO THERAPEUTICS CORPORATION (US) | 2015-05-28 | — | — | US | disclosed |
| US-20130324500-A1 | SPINAL CORD INJURY, INFLAMMATION AND IMMUNE-DISEASE: LOCAL CONTROLLED RELEASE OF THERAPEUTIC AGENTS | INVIVO THERAPEUTICS CORPORATION (US) | 2013-12-05 | — | — | US | disclosed |
| US-20130324509-A1 | SPINAL CORD INJURY, INFLAMMATION, AND IMMUNE-DISEASE: LOCAL CONTROLLED RELEASE OF THERAPEUTIC AGENTS | INVIVO THERAPEUTICS CORPORATION (US) | 2013-12-05 | — | — | US | disclosed |
| US-7855325-B2 | Use of nitric oxide modulators in Agrobacterium-mediated plant transformation | MONSANTO TECHNOLOGY LLC (US) | 2010-12-21 | — | — | US | disclosed |
| US-20100196481-A1 | SPINAL CORD INJURY, INFLAMMATION, AND IMMUNE-DISEASE: LOCAL CONTROLLED RELEASE OF THERAPEUTIC AGENTS | INVIVO THERAPEUTICS CORPORATION (US) | 2010-08-05 | — | — | US | disclosed |
| US-20080274547-A1 | USE OF NITRIC OXIDE MODULATORS IN AGROBACTERIUM-MEDIATED PLANT TRANSFORMATION | MONSANTO TECHNOLOGY LLC | 2008-11-06 | — | — | US | disclosed |