Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3425581 | 0.90 | L3MBTL1 (0.76) | TDP1L3MBTL1MAOBMAOABCHE | |
| SCHEMBL3428392 | 0.85 | L3MBTL1 (0.61) | TDP1L3MBTL1MAOBLMNABCHE | |
| SCHEMBL3423751 | 0.84 | TDP1 (0.74) | TDP1L3MBTL1LMNABCHEGAA | |
| SCHEMBL3425323 | 0.81 | LMNA (0.60) | TDP1L3MBTL1LMNAGAA | |
| SCHEMBL3423150 | 0.78 | MEN1 (0.60) | MAOBMAOASCN9ABCHEPPARA | |
| SCHEMBL3425269 | 0.77 | MAOB (0.54) | MAOBMAOASCN9ABCHEPPARA | |
| SCHEMBL3424913 | 0.77 | MAOB (0.54) | MAOBMAOASCN9ABCHEPPARA | |
| SCHEMBL5020048 | 0.77 | MAOB (0.61) | MAOBMAOASCN9APPARA | |
| SCHEMBL3425467 | 0.76 | MAOB (0.53) | MAOBMAOASCN9ABCHEPPARA | |
| SCHEMBL3423447 | 0.76 | L3MBTL1 (0.76) | TDP1L3MBTL1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7649005-B2 | (R)(4-Pentyloxy-benzyl)-(tetrahydro-furan-2-ylmethyl)-amine; monoamine oxidase inhibitors; neurological, psychiatric, cardiovascular, inflammatory, ophthalmic, urologic, metabolic and gastrointestinal diseases | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2010-01-19 | — | — | US | claimed |
| US-20070135496-A1 | Substituted benzylaminoalkylene heterocycles | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2007-06-14 | — | — | US | claimed |
| EP-1673356-A1 | SUBSTITUTED BENZYLAMINOALKYLENE HETEROCYCLES | Newron Pharmaceuticals S.p.A. (IT) | 2006-06-28 | — | — | EP | claimed |
| WO-2005040138-A1 | SUBSTITUTED BENZYLAMINOALKYLENE HETEROCYCLES | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-05-06 | — | — | WO | claimed |
| EP-1524267-A1 | Substituted benzylaminoalkylene heterocycles | Newron Pharmaceuticals S.p.A. (IT) | 2005-04-20 | — | — | EP | claimed |
| US-7649005-B2 | (R)(4-Pentyloxy-benzyl)-(tetrahydro-furan-2-ylmethyl)-amine; monoamine oxidase inhibitors; neurological, psychiatric, cardiovascular, inflammatory, ophthalmic, urologic, metabolic and gastrointestinal diseases | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2010-01-19 | — | — | US | disclosed |
| US-20070135496-A1 | Substituted benzylaminoalkylene heterocycles | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2007-06-14 | — | — | US | disclosed |
| EP-1673356-A1 | SUBSTITUTED BENZYLAMINOALKYLENE HETEROCYCLES | Newron Pharmaceuticals S.p.A. (IT) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005040138-A1 | SUBSTITUTED BENZYLAMINOALKYLENE HETEROCYCLES | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-05-06 | — | — | WO | disclosed |
| EP-1524267-A1 | Substituted benzylaminoalkylene heterocycles | Newron Pharmaceuticals S.p.A. (IT) | 2005-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135496-A1 | Substituted benzylaminoalkylene heterocycles | HTR7, MAOB, CYP2A7 | TDP1 3447/4885L3MBTL1 3150/4885MAOB 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.