SCHEMBL3427856

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13671614	0.79	PTGER4 (0.55)	PTGER4CNR1SLC16A3MEN1ALDH1A1
	SCHEMBL4252020	0.77	CNR1 (0.48)	PTGER4CNR1MCL1HDAC3HDAC1
	SCHEMBL4250971	0.73	CNR1 (0.46)	PTGER4CNR1MCL1HDAC3HDAC1
	SCHEMBL13865187	0.72	PTGER4 (0.67)	PTGER4CNR1MEN1ALDH1A1KMT2A
	SCHEMBL4245639	0.71	CA12 (0.45)	PTGER4CNR1MCL1HDAC3HDAC1
	SCHEMBL1897336	0.71	PTGER4 (0.59)	PTGER4CNR1SLC16A3ALDH1A1USP30
	SCHEMBL13671617	0.71	CNR1 (0.50)	PTGER4CNR1MCL1
	SCHEMBL4253143	0.71	CNR1 (0.48)	PTGER4CNR1MCL1HDAC3HDAC1
	SCHEMBL3428395	0.71	PTGER4 (0.54)	PTGER4CNR1MCL1MEN1KMT2A
	SCHEMBL3432609	0.71	NPC1 (0.47)	PTGER4CNR1MCL1HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.